Literature DB >> 21490353

Safety of antiviral medication for the treatment of herpes during pregnancy.

So-Hee Kang1, Angela Chua-Gocheco, Pina Bozzo, Adrienne Einarson.   

Abstract

QUESTION: One of my patients is a pregnant woman in her first trimester with a history of recurrent genital herpes. She is concerned about whether use of her antiviral medication will adversely affect her baby. What should I tell her? ANSWER: Studies have shown that the use of acyclovir or valacyclovir is not associated with an increase in birth defects. Limited data exist for famciclovir and therefore it would not be considered a first-line choice for treatment of herpes during pregnancy.

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Year:  2011        PMID: 21490353      PMCID: PMC3076471     

Source DB:  PubMed          Journal:  Can Fam Physician        ISSN: 0008-350X            Impact factor:   3.275


  10 in total

Review 1.  Valaciclovir: a review of its long term utility in the management of genital herpes simplex virus and cytomegalovirus infections.

Authors:  D Ormrod; L J Scott; C M Perry
Journal:  Drugs       Date:  2000-04       Impact factor: 9.546

2.  Antenatal seroprevalence of herpes simplex virus type 2 (HSV-2) in Canadian women: HSV-2 prevalence increases throughout the reproductive years.

Authors:  D M Patrick; M Dawar; D A Cook; M Krajden; H C Ng; M L Rekart
Journal:  Sex Transm Dis       Date:  2001-07       Impact factor: 2.830

3.  Use of acyclovir, valacyclovir, and famciclovir in the first trimester of pregnancy and the risk of birth defects.

Authors:  Björn Pasternak; Anders Hviid
Journal:  JAMA       Date:  2010-08-25       Impact factor: 56.272

Review 4.  Famciclovir: a review of its use in herpes zoster and genital and orolabial herpes.

Authors:  Dene Simpson; Katherine A Lyseng-Williamson
Journal:  Drugs       Date:  2006       Impact factor: 9.546

5.  Trends in herpes simplex virus type 1 and type 2 seroprevalence in the United States.

Authors:  Fujie Xu; Maya R Sternberg; Benny J Kottiri; Geraldine M McQuillan; Francis K Lee; Andre J Nahmias; Stuart M Berman; Lauri E Markowitz
Journal:  JAMA       Date:  2006-08-23       Impact factor: 56.272

6.  Neonatal herpes simplex virus infections in Canada: results of a 3-year national prospective study.

Authors:  Rhonda Y Kropp; Thomas Wong; Louise Cormier; Allison Ringrose; Sandra Burton; Joanne E Embree; Marc Steben
Journal:  Pediatrics       Date:  2006-06       Impact factor: 7.124

7.  Recurrence rates in genital herpes after symptomatic first-episode infection.

Authors:  J Benedetti; L Corey; R Ashley
Journal:  Ann Intern Med       Date:  1994-12-01       Impact factor: 25.391

8.  Regional distribution of antibodies to herpes simplex virus type 1 (HSV-1) and HSV-2 in men and women in Ontario, Canada.

Authors:  Michelle Howard; John W Sellors; Dan Jang; Noah J Robinson; Margaret Fearon; Janusz Kaczorowski; Max Chernesky
Journal:  J Clin Microbiol       Date:  2003-01       Impact factor: 5.948

Review 9.  Third trimester antiviral prophylaxis for preventing maternal genital herpes simplex virus (HSV) recurrences and neonatal infection.

Authors:  L M Hollier; G D Wendel
Journal:  Cochrane Database Syst Rev       Date:  2008-01-23

Review 10.  Herpes simplex virus infection in pregnancy and in neonate: status of art of epidemiology, diagnosis, therapy and prevention.

Authors:  Elena Anzivino; Daniela Fioriti; Monica Mischitelli; Anna Bellizzi; Valentina Barucca; Fernanda Chiarini; Valeria Pietropaolo
Journal:  Virol J       Date:  2009-04-06       Impact factor: 4.099

  10 in total
  7 in total

Review 1.  Herpes Genitalis: Diagnosis, Treatment and Prevention.

Authors:  A Sauerbrei
Journal:  Geburtshilfe Frauenheilkd       Date:  2016-10-18       Impact factor: 2.915

Review 2.  Glycoprotein targeted therapeutics: a new era of anti-herpes simplex virus-1 therapeutics.

Authors:  Thessicar E Antoine; Paul J Park; Deepak Shukla
Journal:  Rev Med Virol       Date:  2013-02-26       Impact factor: 6.989

3.  Ribonucleotide reductase inhibitors hydroxyurea, didox, and trimidox inhibit human cytomegalovirus replication in vitro and synergize with ganciclovir.

Authors:  Sukhada Bhave; Howard Elford; Michael A McVoy
Journal:  Antiviral Res       Date:  2013-08-06       Impact factor: 5.970

Review 4.  Herpes simplex virus encephalitis in pregnancy - a case report and review of reported patients in the literature.

Authors:  Katherine C Dodd; Benedict D Michael; Besa Ziso; Bode Williams; Ray Borrow; Anita Krishnan; Tom Solomon
Journal:  BMC Res Notes       Date:  2015-04-01

Review 5.  Optimal management of genital herpes: current perspectives.

Authors:  Andreas Sauerbrei
Journal:  Infect Drug Resist       Date:  2016-06-13       Impact factor: 4.003

6.  Empirical treatment with parenteral acyclovir in a child with herpes simplex virus hepatitis and acute lymphoblastic leukemia.

Authors:  Nesreen A Faqih; Mahmoud A Alfaqih; Khadra Salami; Brian Herron; Iyad Sultan; Maysa Al-Hussaini
Journal:  IDCases       Date:  2018-02-21

7.  Herbal Gel Formulation Developed for Anti-Human Immunodeficiency Virus (HIV)-1 Activity Also Inhibits In Vitro HSV-2 Infection.

Authors:  Nripendra Nath Mishra; Ajay Kesharwani; Aakanksha Agarwal; Suja Kizhiyedath Polachira; Reshmi Nair; Satish Kumar Gupta
Journal:  Viruses       Date:  2018-10-24       Impact factor: 5.048

  7 in total

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