BACKGROUND: Hypersomnia in inter-episode bipolar disorder has been minimally researched. The current study sought to document the prevalence of hypersomnia in a sample of inter-episode patients with bipolar disorder and to examine the relationship between hypersomnia and future bipolar depressive symptoms. METHODS: A total of 56 individuals with bipolar disorder (51 type I+5 type II) who were currently inter-episode, along with 55 non-psychiatric controls, completed a baseline assessment, including semi-structured interviews for psychiatric diagnoses, sleep disorders, and a battery of indices that included assessment of hypersomnia. Approximately 6 months later, participants were recontacted by telephone and mood was re-evaluated. RESULTS: Three of six indices suggested that approximately 25% of participants with bipolar disorder endorsed symptoms of hypersomnia in the inter-episode period. Within the bipolar group, hypersomnia in the inter-episode period was associated with future depressive symptoms. This finding was independent of baseline depressive symptoms and medication use. LIMITATIONS: Small sample size and concurrent psychopharmacology in the bipolar sample. DISCUSSION: Though no gold standard measure for hypersomnia currently exists, this research takes a step towards identifying a clinically and empirically useful hypersomnia assessment. This study demonstrates that hypersomnia in the inter-episode period of bipolar disorder relates to future depressive symptoms, and adds to the growing body of evidence on the importance of inter-episode symptoms predicting bipolar relapse. Published by Elsevier B.V.
BACKGROUND:Hypersomnia in inter-episode bipolar disorder has been minimally researched. The current study sought to document the prevalence of hypersomnia in a sample of inter-episode patients with bipolar disorder and to examine the relationship between hypersomnia and future bipolar depressive symptoms. METHODS: A total of 56 individuals with bipolar disorder (51 type I+5 type II) who were currently inter-episode, along with 55 non-psychiatric controls, completed a baseline assessment, including semi-structured interviews for psychiatric diagnoses, sleep disorders, and a battery of indices that included assessment of hypersomnia. Approximately 6 months later, participants were recontacted by telephone and mood was re-evaluated. RESULTS: Three of six indices suggested that approximately 25% of participants with bipolar disorder endorsed symptoms of hypersomnia in the inter-episode period. Within the bipolar group, hypersomnia in the inter-episode period was associated with future depressive symptoms. This finding was independent of baseline depressive symptoms and medication use. LIMITATIONS: Small sample size and concurrent psychopharmacology in the bipolar sample. DISCUSSION: Though no gold standard measure for hypersomnia currently exists, this research takes a step towards identifying a clinically and empirically useful hypersomnia assessment. This study demonstrates that hypersomnia in the inter-episode period of bipolar disorder relates to future depressive symptoms, and adds to the growing body of evidence on the importance of inter-episode symptoms predicting bipolar relapse. Published by Elsevier B.V.
Authors: K D Denicoff; G S Leverich; W A Nolen; A J Rush; S L McElroy; P E Keck; T Suppes; L L Altshuler; R Kupka; M A Frye; J Hatef; M A Brotman; R M Post Journal: Psychol Med Date: 2000-11 Impact factor: 7.723
Authors: W G Frankle; R H Perlis; T Deckersbach; L D Grandin; S M Gray; G S Sachs; A A Nierenberg Journal: Psychol Med Date: 2002-11 Impact factor: 7.723
Authors: K A Kaplan; E L McGlinchey; A Soehner; A Gershon; L S Talbot; P Eidelman; J Gruber; A G Harvey Journal: Psychol Med Date: 2014-12-17 Impact factor: 7.723
Authors: Allison G Harvey; Adriane M Soehner; Kate A Kaplan; Kerrie Hein; Jason Lee; Jennifer Kanady; Descartes Li; Sophia Rabe-Hesketh; Terence A Ketter; Thomas C Neylan; Daniel J Buysse Journal: J Consult Clin Psychol Date: 2015-01-26