Literature DB >> 21486834

The missing Akt in the mechanical regulation of skeletal muscle mTORC1 signalling and growth.

Blake B Rasmussen1.   

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Year:  2011        PMID: 21486834      PMCID: PMC3099007          DOI: 10.1113/jphysiol.2011.207837

Source DB:  PubMed          Journal:  J Physiol        ISSN: 0022-3751            Impact factor:   5.182


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  7 in total

1.  Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo.

Authors:  S C Bodine; T N Stitt; M Gonzalez; W O Kline; G L Stover; R Bauerlein; E Zlotchenko; A Scrimgeour; J C Lawrence; D J Glass; G D Yancopoulos
Journal:  Nat Cell Biol       Date:  2001-11       Impact factor: 28.824

2.  High-frequency electrically stimulated skeletal muscle contractions increase p70s6k phosphorylation independent of known IGF-I sensitive signaling pathways.

Authors:  Sarah Witkowski; Richard M Lovering; Espen E Spangenburg
Journal:  FEBS Lett       Date:  2010-05-11       Impact factor: 4.124

3.  Early activation of mTORC1 signalling in response to mechanical overload is independent of phosphoinositide 3-kinase/Akt signalling.

Authors:  Mitsunori Miyazaki; John J McCarthy; Mark J Fedele; Karyn A Esser
Journal:  J Physiol       Date:  2011-02-07       Impact factor: 5.182

4.  Rapamycin administration in humans blocks the contraction-induced increase in skeletal muscle protein synthesis.

Authors:  Micah J Drummond; Christopher S Fry; Erin L Glynn; Hans C Dreyer; Shaheen Dhanani; Kyle L Timmerman; Elena Volpi; Blake B Rasmussen
Journal:  J Physiol       Date:  2009-02-02       Impact factor: 5.182

5.  The role of phosphoinositide 3-kinase and phosphatidic acid in the regulation of mammalian target of rapamycin following eccentric contractions.

Authors:  T K O'Neil; L R Duffy; J W Frey; T A Hornberger
Journal:  J Physiol       Date:  2009-05-26       Impact factor: 5.182

6.  A functional insulin-like growth factor receptor is not necessary for load-induced skeletal muscle hypertrophy.

Authors:  Espen E Spangenburg; Derek Le Roith; Chris W Ward; Sue C Bodine
Journal:  J Physiol       Date:  2007-11-01       Impact factor: 5.182

7.  Aging impairs contraction-induced human skeletal muscle mTORC1 signaling and protein synthesis.

Authors:  Christopher S Fry; Micah J Drummond; Erin L Glynn; Jared M Dickinson; David M Gundermann; Kyle L Timmerman; Dillon K Walker; Shaheen Dhanani; Elena Volpi; Blake B Rasmussen
Journal:  Skelet Muscle       Date:  2011-03-02       Impact factor: 4.912

  7 in total
  3 in total

Review 1.  Considerations on mTOR regulation at serine 2448: implications for muscle metabolism studies.

Authors:  Vandré Casagrande Figueiredo; James F Markworth; David Cameron-Smith
Journal:  Cell Mol Life Sci       Date:  2017-02-20       Impact factor: 9.261

Review 2.  Regulation of muscle protein synthesis and the effects of catabolic states.

Authors:  Bradley S Gordon; Andrew R Kelleher; Scot R Kimball
Journal:  Int J Biochem Cell Biol       Date:  2013-06-12       Impact factor: 5.085

3.  Application of the [γ-32P] ATP kinase assay to study anabolic signaling in human skeletal muscle.

Authors:  Chris McGlory; Amanda White; Caroline Treins; Barry Drust; Graeme L Close; Don P M Maclaren; Iain T Campbell; Andrew Philp; Simon Schenk; James P Morton; D Lee Hamilton
Journal:  J Appl Physiol (1985)       Date:  2014-01-16
  3 in total

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