Literature DB >> 21486026

Asymmetic organocatalytic 1,3-dipolar cycloaddition of azomethine ylide to methyl 2-(2-nitrophenyl)acrylate for the synthesis of diastereoisomers of spirotryprostatin A.

Mou-Nuo Cheng1, Hao Wang, Liu-Zhu Gong.   

Abstract

The total synthesis of two diastereomers of spirotryprostatin A has been established starting with an asymmetric 1,3-dipolar cycloaddition of methyl 2-(2-nitrophenyl)acrylate with azomethine ylides catalyzed by a Brønsted acid.

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Year:  2011        PMID： 21486026     DOI： 10.1021/ol200652j

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  3 in total

1.  Enantioselective organo-SOMO cycloadditions: a catalytic approach to complex pyrrolidines from olefins and aldehydes.

Authors:  Nathan T Jui; Jeffrey A O Garber; Fernanda Gadini Finelli; David W C MacMillan
Journal:  J Am Chem Soc       Date:  2012-07-10       Impact factor: 15.419

2.  Synthesis, Antimicrobial Activity, Structure-Activity Relationship, and Molecular Docking Studies of Indole Diketopiperazine Alkaloids.

Authors:  Bin Jia; Yang-Min Ma; Bin Liu; Pu Chen; Yan Hu; Rui Zhang
Journal:  Front Chem       Date:  2019-11-29       Impact factor: 5.221

3.  A new entry to azomethine ylides from allylic amines and glyoxals: shifting the reliance on amino ester precursors.

Authors:  Natalie K Machamer; Xiaoxi Liu; Stephen P Waters
Journal:  Org Lett       Date:  2014-09-23       Impact factor: 6.005
  3 in total

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