| Literature DB >> 2148520 |
C Singer1, J Sanchez-Ramos, W J Weiner.
Abstract
We report a patient with Down's syndrome (DS) who developed progressive parkinsonian symptomatology at the age of 43 years. His parkinsonism was responsive to levodopa/carbidopa, but he developed end of dose wearing off. We discuss basal ganglia and dopamine abnormalities in DS and suggest that DS may be associated with parkinsonism.Entities:
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Year: 1990 PMID： 2148520 DOI： 10.1159/000117355
Source DB: PubMed Journal: Eur Neurol ISSN： 0014-3022 Impact factor: 1.710