| Literature DB >> 21484673 |
Dan Du1, Lei Fang, Jing Qu, Shishan Yu, Shuanggang Ma, Haining Lv, Jing Liu, Yuanyan Liu, Jiaming Wang, Xiaojing Wang.
Abstract
Phytochemical investigation of the EtOH extract of the leaves of Erythrophleum fordii led to the isolation of two oleanane-type triterpene saponins (1-2) and five cassaine-type diterpenoids (4-8) along with one known methyl 3 β-hydroxy-erythrosuamate (3). Their structures were established by extensive NMR, as well as ESI-MS analyses and acid hydrolysis. Biological evaluation of compounds 3- 8 against five human cancer cell lines revealed that compounds 5-7 exhibited potent cytotoxic activity with IC₅₀ values ranging from 1.51 to 8.68 µM. © Georg Thieme Verlag KG Stuttgart · New York.Entities:
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Year: 2011 PMID： 21484673 DOI： 10.1055/s-0030-1270992
Source DB: PubMed Journal: Planta Med ISSN： 0032-0943 Impact factor: 3.352