Literature DB >> 21481596

Boronated unnatural cyclic amino acids as potential delivery agents for neutron capture therapy.

George W Kabalka1, Aarif L Shaikh, Rolf F Barth, Tianyao Huo, Weilian Yang, Pamela M Gordnier, Subhash Chandra.   

Abstract

Boron delivery characteristics of cis and trans isomers of a boronated unnatural amino acid, 1-amino-3-boronocyclopentanecarboxylic acid (ABCPC) were tested in the B16 mouse model for human melanoma. Both ABCPC isomers delivered comparable boron to B16 melanoma tumor cells as L-p-boronophenylalanine (BPA). Secondary ion mass spectrometry (SIMS) analysis revealed the presence of boron throughout the tumor from these compounds, and a near homogeneous distribution between the nucleus and cytoplasm of B16 cells grown in vitro. These encouraging observations support further studies of these new boron carriers in BNCT. Copyright Â
© 2011 Elsevier Ltd. All rights reserved.

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Year:  2011        PMID： 21481596      PMCID： PMC3135783          DOI： 10.1016/j.apradiso.2011.03.035

Source DB:  PubMed          Journal:  Appl Radiat Isot        ISSN： 0969-8043            Impact factor:   1.513


  11 in total

1.  Subcellular imaging by dynamic SIMS ion microscopy.

Authors:  S Chandra; D R Smith; G H Morrison
Journal:  Anal Chem       Date:  2000-02-01       Impact factor: 6.986

2.  Unilamellar liposomes with enhanced boron content.

Authors:  Tiejun Li; Julie Hamdi; M Frederick Hawthorne
Journal:  Bioconjug Chem       Date:  2006 Jan-Feb       Impact factor: 4.774

3.  Imaging intracellular elemental distribution and ion fluxes in cultured cells using ion microscopy: a freeze-fracture methodology.

Authors:  S Chandra; G H Morrison; C C Wolcott
Journal:  J Microsc       Date:  1986-10       Impact factor: 1.758

4.  Quantitative imaging of chemical composition in single cells by secondary ion mass spectrometry: cisplatin affects calcium stores in renal epithelial cells.

Authors:  Subhash Chandra
Journal:  Methods Mol Biol       Date:  2010

Review 5.  Boron neutron capture therapy of cancer: current status and future prospects.

Authors:  Rolf F Barth; Jeffrey A Coderre; M Graça H Vicente; Thomas E Blue
Journal:  Clin Cancer Res       Date:  2005-06-01       Impact factor: 12.531

6.  Boron neutron capture therapy of intracerebral melanoma using boronophenylalanine as a capture agent.

Authors:  K Z Matalka; M Q Bailey; R F Barth; A E Staubus; A H Soloway; M L Moeschberger; J A Coderre; E K Rofstad
Journal:  Cancer Res       Date:  1993-07-15       Impact factor: 12.701

7.  Biological evaluation of boronated unnatural amino acids as new boron carriers.

Authors:  G W Kabalka; M-L Yao; S R Marepally; S Chandra
Journal:  Appl Radiat Isot       Date:  2009-04-02       Impact factor: 1.513

8.  The Monte Carlo simulation of the biological effect of the 10B(n, alpha)7Li reaction in cells and tissue and its implication for boron neutron capture therapy.

Authors:  D Gabel; S Foster; R G Fairchild
Journal:  Radiat Res       Date:  1987-07       Impact factor: 2.841

9.  The syntheses and in vivo biodistribution of novel boronated unnatural amino acids.

Authors:  G W Kabalka; Z Z Wu; M-L Yao; N Natarajan
Journal:  Appl Radiat Isot       Date:  2004-11       Impact factor: 1.513

Review 10.  The synthesis and use of boronated amino acids for boron neutron capture therapy.

Authors:  George W Kabalka; Min-Liang Yao
Journal:  Anticancer Agents Med Chem       Date:  2006-03       Impact factor: 2.505
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  7 in total

1.  Evaluation of unnatural cyclic amino acids as boron delivery agents for treatment of melanomas and gliomas.

Authors:  Rolf F Barth; George W Kabalka; Weilian Yang; Tianyao Huo; Robin J Nakkula; Aarif L Shaikh; Syed A Haider; Subhash Chandra
Journal:  Appl Radiat Isot       Date:  2013-12-12       Impact factor: 1.513

Review 2.  Mass spectrometry imaging and profiling of single cells.

Authors:  Eric J Lanni; Stanislav S Rubakhin; Jonathan V Sweedler
Journal:  J Proteomics       Date:  2012-03-29       Impact factor: 4.044

Review 3.  Boron chemicals in diagnosis and therapeutics.

Authors:  Bhaskar C Das; Pritam Thapa; Radha Karki; Caroline Schinke; Sasmita Das; Suman Kambhampati; Sushanta K Banerjee; Peter Van Veldhuizen; Amit Verma; Louis M Weiss; Todd Evans
Journal:  Future Med Chem       Date:  2013-04       Impact factor: 3.808

4.  Evaluation of a novel sodium borocaptate-containing unnatural amino acid as a boron delivery agent for neutron capture therapy of the F98 rat glioma.

Authors:  Gen Futamura; Shinji Kawabata; Naosuke Nonoguchi; Ryo Hiramatsu; Taichiro Toho; Hiroki Tanaka; Shin-Ichiro Masunaga; Yoshihide Hattori; Mitsunori Kirihata; Koji Ono; Toshihiko Kuroiwa; Shin-Ichi Miyatake
Journal:  Radiat Oncol       Date:  2017-01-23       Impact factor: 3.481

5.  Synthesis and Evaluation of Dodecaboranethiol Containing Kojic Acid (KA-BSH) as a Novel Agent for Boron Neutron Capture Therapy.

Authors:  Koji Takeuchi; Yoshihide Hattori; Shinji Kawabata; Gen Futamura; Ryo Hiramatsu; Masahiko Wanibuchi; Hiroki Tanaka; Shin-Ichiro Masunaga; Koji Ono; Shin-Ichi Miyatake; Mitsunori Kirihata
Journal:  Cells       Date:  2020-06-25       Impact factor: 6.600

Review 6.  Boron delivery agents for neutron capture therapy of cancer.

Authors:  Rolf F Barth; Peng Mi; Weilian Yang
Journal:  Cancer Commun (Lond)       Date:  2018-06-19

7.  Aza-BODIPY: A New Vector for Enhanced Theranostic Boron Neutron Capture Therapy Applications.

Authors:  Ghadir Kalot; Amélie Godard; Benoît Busser; Jacques Pliquett; Mans Broekgaarden; Vincent Motto-Ros; Karl David Wegner; Ute Resch-Genger; Ulli Köster; Franck Denat; Jean-Luc Coll; Ewen Bodio; Christine Goze; Lucie Sancey
Journal:  Cells       Date:  2020-08-25       Impact factor: 6.600
  7 in total

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