Literature DB >> 21481496

Synthesis of 2-aziridinyl phosphonates by modified Gabriel-Cromwell reaction and their antibacterial activities.

Özdemir Doğan1, Hakan Babiz, Ayşe Gül Gözen, Songül Budak.   

Abstract

A set of new aziridinyl phosphonates (4a-g) were synthesized by using the Gabriel-Cromwell reaction and its modified version developed in this study and their structures confirmed by HRMS, IR, and NMR spectra. All the compounds were screened for their antibacterial activity. They all showed comparable moderate to good growth inhibitory activity in reference to ampicillin and streptomycin.
Copyright © 2011 Elsevier Masson SAS. All rights reserved.

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Year:  2011        PMID: 21481496     DOI: 10.1016/j.ejmech.2011.03.037

Source DB:  PubMed          Journal:  Eur J Med Chem        ISSN: 0223-5234            Impact factor:   6.514


  4 in total

1.  A structural insight into the P1S1 binding mode of diaminoethylphosphonic and phosphinic acids, selective inhibitors of alanine aminopeptidases.

Authors:  Ewelina Węglarz-Tomczak; Łukasz Berlicki; Małgorzata Pawełczak; Bogusław Nocek; Andrzej Joachimiak; Artur Mucha
Journal:  Eur J Med Chem       Date:  2016-04-09       Impact factor: 6.514

2.  Enantioselective dearomatization of isoquinolines by anion-binding catalysis en route to cyclic α-aminophosphonates.

Authors:  Abhijnan Ray Choudhury; Santanu Mukherjee
Journal:  Chem Sci       Date:  2016-08-19       Impact factor: 9.825

3.  Synthesis and Evaluation of Biological Activities of Aziridine Derivatives of Urea and Thiourea.

Authors:  Aleksandra Kowalczyk; Adam M Pieczonka; Michał Rachwalski; Stanisław Leśniak; Paweł Stączek
Journal:  Molecules       Date:  2017-12-25       Impact factor: 4.411

4.  A novel approach for obtaining α,β-diaminophosphonates bearing structurally diverse side chains and their interactions with transition metal ions studied by ITC.

Authors:  Paweł Lenartowicz; Danuta Witkowska; Beata Żyszka-Haberecht; Błażej Dziuk; Krzysztof Ejsmont; Jolanta Świątek-Kozłowska; Paweł Kafarski
Journal:  RSC Adv       Date:  2020-06-23       Impact factor: 4.036

  4 in total

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