Smriti Agrawal1, Anjoo Agarwal, Vinita Das. 1. Department of Obstetrics and Gynecology, Chhatrapati Shahuji Maharaj Medical University, Lucknow, India. smritijainagrawal@rediffmail.com
Abstract
AIM: This study was undertaken to evaluate the impact of grandmultiparity on obstetric outcome in a low resource setting. MATERIAL & METHODS: Two hundred and eighty-two antenatal grandmultiparous women (parity ≥ 4) were compared with consecutive 564 antenatal women with parity 1-3. RESULTS: There were 13 403 deliveries over the study period from Jan 2006-December 2008 at CSMMU, Lucknow. The prevalence of grandmultipara was 2.3%. Grandmultipara were older (P < 0.001) and more commonly from rural areas (P < 0.001) as compared to the control group. The percentage of Muslims among grandmultipara (23.8%) was higher than among controls (16.5%), P < 0.01. Grandmultipara had significantly higher prevalence of anemia (P < 0.001), malpresentation (P = 0.01) and rupture uterus (P < 0.001). Abruptio placenta, placenta previa and obstructed labor were seen more often in grandmultipara, and the difference was statistically significant (P < 0.01 in each group). There was no difference in terms of mode of delivery, sex of newborn or the prevalence of low birthweight (<2.5 kg) babies. Stillbirths were more common in grandmultiparas (P < 0.001). There was one maternal death in the study group. CONCLUSION: Grandmultiparity continues to be of grave concern with an adverse impact on obstetric and perinatal outcome.
AIM: This study was undertaken to evaluate the impact of grandmultiparity on obstetric outcome in a low resource setting. MATERIAL & METHODS: Two hundred and eighty-two antenatal grandmultiparous women (parity ≥ 4) were compared with consecutive 564 antenatal women with parity 1-3. RESULTS: There were 13 403 deliveries over the study period from Jan 2006-December 2008 at CSMMU, Lucknow. The prevalence of grandmultipara was 2.3%. Grandmultipara were older (P < 0.001) and more commonly from rural areas (P < 0.001) as compared to the control group. The percentage of Muslims among grandmultipara (23.8%) was higher than among controls (16.5%), P < 0.01. Grandmultipara had significantly higher prevalence of anemia (P < 0.001), malpresentation (P = 0.01) and rupture uterus (P < 0.001). Abruptio placenta, placenta previa and obstructed labor were seen more often in grandmultipara, and the difference was statistically significant (P < 0.01 in each group). There was no difference in terms of mode of delivery, sex of newborn or the prevalence of low birthweight (<2.5 kg) babies. Stillbirths were more common in grandmultiparas (P < 0.001). There was one maternal death in the study group. CONCLUSION: Grandmultiparity continues to be of grave concern with an adverse impact on obstetric and perinatal outcome.
Authors: David A Schirmer; Aniket D Kulkarni; Yujia Zhang; Jennifer F Kawwass; Sheree L Boulet; Dmitry M Kissin Journal: Fertil Steril Date: 2020-07-14 Impact factor: 7.329