H-C Hu 1 , Y-H Liu , Y-C Wu , M-J Hsieh , Y-K Chao , C-Y Wu , P-J Ko , C-Y Liu Show Affiliations »
Abstract
OBJECTIVES: The present study aimed to determine whether stent diameter influences granulation tissue formation following stent placement for major airway stenosis. PATIENTS AND METHODS: Forty-two stent procedures (32 tracheal stents, 3 carinal stents, and 7 bronchial stents) were performed in 40 patients. Seventy-nine stent edge regions (62 tracheal, 17 bronchial stents) were evaluated in this study. RESULTS: Granulation tissue formation was encountered in 11 patients (28.21%). Of the 34 upper ends of evaluated tracheal stents, granulation tissue formation was observed in 6 (17.65%), whereas granulation tissue formation was observed in 2 (7.14%) of the 28 lower ends of tracheal stents evaluated. Of the 17 bronchial stent edge regions, granulation tissue formation occurred in 3 (17.65%) ( P = 0.4352). The rate of granulation tissue formation was higher in those patients with a stent-to-airway diameter ratio of > 90% ( P < 0.0001). Receiver operating characteristic curve analysis further demonstrated that a cut-off stent-to-airway diameter ratio of 90% was effective in predicting granulation tissue formation (AUC: 0.897, Std. error = 0.036, P < 0.0001, 95% CI = 0827-0.968, n = 79). CONCLUSIONS: A stent-to-airway diameter ratio of 90% was found to be the critical cut-off point for predicting granulation tissue formation. Therefore, the optimal stent-to-airway diameter ratio should be ascertained before stent placement. © Georg Thieme Verlag KG Stuttgart · New York.
OBJECTIVES: The present study aimed to determine whether stent diameter influences granulation tissue formation following stent placement for major airway stenosis. PATIENTS AND METHODS: Forty-two stent procedures (32 tracheal stents, 3 carinal stents, and 7 bronchial stents) were performed in 40 patients . Seventy-nine stent edge regions (62 tracheal, 17 bronchial stents) were evaluated in this study. RESULTS: Granulation tissue formation was encountered in 11 patients (28.21%). Of the 34 upper ends of evaluated tracheal stents, granulation tissue formation was observed in 6 (17.65%), whereas granulation tissue formation was observed in 2 (7.14%) of the 28 lower ends of tracheal stents evaluated. Of the 17 bronchial stent edge regions, granulation tissue formation occurred in 3 (17.65%) ( P = 0.4352). The rate of granulation tissue formation was higher in those patients with a stent-to-airway diameter ratio of > 90% ( P < 0.0001). Receiver operating characteristic curve analysis further demonstrated that a cut-off stent-to-airway diameter ratio of 90% was effective in predicting granulation tissue formation (AUC: 0.897, Std. error = 0.036, P < 0.0001, 95% CI = 0827-0.968, n = 79). CONCLUSIONS: A stent-to-airway diameter ratio of 90% was found to be the critical cut-off point for predicting granulation tissue formation. Therefore, the optimal stent-to-airway diameter ratio should be ascertained before stent placement. © Georg Thieme Verlag KG Stuttgart · New York.
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Year: 2011
PMID： 21480137 DOI： 10.1055/s-0030-1250667
Source DB: PubMed Journal: Thorac Cardiovasc Surg ISSN： 0171-6425 Impact factor: 1.827