Literature DB >> 21479794

The placebo phenomenon and medical ethics: rethinking the relationship between informed consent and risk-benefit assessment.

Franklin G Miller1, Luana Colloca.   

Abstract

It has been presumed within bioethics that the benefits and risks of treatments can be assessed independently of information disclosure to patients as part of the informed consent process. Research on placebo and nocebo effects indicates that this is not true for symptomatic treatments. The benefits and risks that patients experience from symptomatic treatments can be shaped powerfully by information about these treatments provided by clinicians. In this paper we discuss the implications of placebo and nocebo research for risk-benefit assessment and informed consent.

Entities:  

Mesh：

Year:  2011        PMID： 21479794     DOI： 10.1007/s11017-011-9179-8

Source DB:  PubMed          Journal:  Theor Med Bioeth        ISSN： 1386-7415


  29 in total

1.  Response expectancies in placebo analgesia and their clinical relevance.

Authors:  Antonella Pollo; Martina Amanzio; Anna Arslanian; Caterina Casadio; Giuliano Maggi; Fabrizio Benedetti
Journal:  Pain       Date:  2001-07       Impact factor: 6.961

2.  Effects of suggestion and conditioning on the action of chemical agents in human subjects; the pharmacology of placebos.

Authors:  S WOLF
Journal:  J Clin Invest       Date:  1950-01       Impact factor: 14.808

3.  The legitimacy of placebo treatments in clinical practice: evidence and ethics.

Authors:  Franklin G Miller; Luana Colloca
Journal:  Am J Bioeth       Date:  2009-12       Impact factor: 11.229

4.  Understanding and harnessing placebo effects: clearing away the underbrush.

Authors:  Franklin G Miller; Howard Brody
Journal:  J Med Philos       Date:  2011-01-10

5.  Framing effects on expectations, decisions, and side effects experienced: the case of influenza immunization.

Authors:  A M O'Connor; R A Pennie; R E Dales
Journal:  J Clin Epidemiol       Date:  1996-11       Impact factor: 6.437

6.  Words as scalpels: transmitting evidence in the clinical dialogue.

Authors:  S J Reiser
Journal:  Ann Intern Med       Date:  1980-06       Impact factor: 25.391

Review 7.  Overt versus covert treatment for pain, anxiety, and Parkinson's disease.

Authors:  Luana Colloca; Leonardo Lopiano; Michele Lanotte; Fabrizio Benedetti
Journal:  Lancet Neurol       Date:  2004-11       Impact factor: 44.182

8.  A randomized trial of vertebroplasty for painful osteoporotic vertebral fractures.

Authors:  Rachelle Buchbinder; Richard H Osborne; Peter R Ebeling; John D Wark; Peter Mitchell; Chris Wriedt; Stephen Graves; Margaret P Staples; Bridie Murphy
Journal:  N Engl J Med       Date:  2009-08-06       Impact factor: 91.245

9.  Components of placebo effect: randomised controlled trial in patients with irritable bowel syndrome.

Authors:  Ted J Kaptchuk; John M Kelley; Lisa A Conboy; Roger B Davis; Catherine E Kerr; Eric E Jacobson; Irving Kirsch; Rosa N Schyner; Bong Hyun Nam; Long T Nguyen; Min Park; Andrea L Rivers; Claire McManus; Efi Kokkotou; Douglas A Drossman; Peter Goldman; Anthony J Lembo
Journal:  BMJ       Date:  2008-04-03

10.  Placebos without deception: a randomized controlled trial in irritable bowel syndrome.

Authors:  Ted J Kaptchuk; Elizabeth Friedlander; John M Kelley; M Norma Sanchez; Efi Kokkotou; Joyce P Singer; Magda Kowalczykowski; Franklin G Miller; Irving Kirsch; Anthony J Lembo
Journal:  PLoS One       Date:  2010-12-22       Impact factor: 3.240
View more
  29 in total

1.  The placebo phenomenon: implications for the ethics of shared decision-making.

Authors:  Howard Brody; Luana Colloca; Franklin G Miller
Journal:  J Gen Intern Med       Date:  2012-01-19       Impact factor: 5.128

2.  The placebo response: science versus ethics and the vulnerability of the patient.

Authors:  Fabrizio Benedetti
Journal:  World Psychiatry       Date:  2012-06       Impact factor: 49.548

Review 3.  The placebo response in medicine: minimize, maximize or personalize?

Authors:  Paul Enck; Ulrike Bingel; Manfred Schedlowski; Winfried Rief
Journal:  Nat Rev Drug Discov       Date:  2013-03       Impact factor: 84.694

4.  Placebos, Full Disclosure, and Trust: The Risks and Benefits of Disclosing Risks and Benefits.

Authors:  Peter H Schwartz
Journal:  Am J Bioeth       Date:  2015       Impact factor: 11.229

5.  Mirroring everyday clinical practice in clinical trial design: a new concept to improve the external validity of randomized double-blind placebo-controlled trials in the pharmacological treatment of major depression.

Authors:  Emanuel Severus; Florian Seemüller; Michael Berger; Sandra Dittmann; Michael Obermeier; Andrea Pfennig; Michael Riedel; Sophia Frangou; Hans-Jürgen Möller; Michael Bauer
Journal:  BMC Med       Date:  2012-07-02       Impact factor: 8.775

6.  Tell Me the Truth and I Will Not Be Harmed: Informed Consents and Nocebo Effects.

Authors:  Luana Colloca
Journal:  Am J Bioeth       Date:  2017-06       Impact factor: 11.229

Review 7.  The nocebo effect and its relevance for clinical practice.

Authors:  Luana Colloca; Franklin G Miller
Journal:  Psychosom Med       Date:  2011-08-23       Impact factor: 4.312

8.  Framing for success: nocebo effects in thoracic surgery.

Authors:  Judson B Williams; Robert M Sade; Thomas A D'Amico
Journal:  Ann Thorac Surg       Date:  2012-12-25       Impact factor: 4.330

Review 9.  Nocebo phenomena in medicine: their relevance in everyday clinical practice.

Authors:  Winfried Häuser; Ernil Hansen; Paul Enck
Journal:  Dtsch Arztebl Int       Date:  2012-06-29       Impact factor: 5.594

Review 10.  Placebo and the new physiology of the doctor-patient relationship.

Authors:  Fabrizio Benedetti
Journal:  Physiol Rev       Date:  2013-07       Impact factor: 37.312
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.