Literature DB >> 2147956

Synthesis and dopamine receptor affinity of (R)-(-)-2-fluoro-N-n-propylnorapomorphine: a highly potent and selective dopamine D2 agonist.

J L Neumeyer1, Y G Gao, N S Kula, R J Baldessarini.   

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Year:  1990        PMID： 2147956     DOI： 10.1021/jm00174a002

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


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  6 in total

1.  Pharmacological characterization of 2-methoxy-N-propylnorapomorphine's interactions with D2 and D3 dopamine receptors.

Authors:  Mette Skinbjerg; Yoon Namkung; Christer Halldin; Robert B Innis; David R Sibley
Journal:  Synapse       Date:  2009-06       Impact factor: 2.562

Review 2.  Agonist high- and low-affinity states of dopamine D₂ receptors: methods of detection and clinical implications.

Authors:  Jan-Peter van Wieringen; Jan Booij; Vladimir Shalgunov; Philip Elsinga; Martin C Michel
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2012-12-09       Impact factor: 3.000

3.  Convenient synthesis of 18F-radiolabeled R-(-)-N-n-propyl-2-(3-fluoropropanoxy-11-hydroxynoraporphine.

Authors:  Anna W Sromek; Shaohui Zhang; Vamsidhar Akurathi; Alan B Packard; Wei Li; David Alagille; Thomas J Morley; Ronald Baldwin; Gilles Tamagnan; John L Neumeyer
Journal:  J Labelled Comp Radiopharm       Date:  2014-11-17       Impact factor: 1.921

4.  Synthesis and Evaluation of Fluorinated Aporphines: Potential Positron Emission Tomography Ligands for D2 Receptors

Authors:  Anna W Sromek; Yu-Gui Si; Tangzhi Zhang; Susan R George; Philip Seeman; John L Neumeyer
Journal:  ACS Med Chem Lett       Date:  2011-03-10       Impact factor: 4.345

5.  D2 dopamine receptor internalization prolongs the decrease of radioligand binding after amphetamine: a PET study in a receptor internalization-deficient mouse model.

Authors:  Mette Skinbjerg; Jeih-San Liow; Nicholas Seneca; Jinsoo Hong; Shuiyu Lu; Annika Thorsell; Markus Heilig; Victor W Pike; Christer Halldin; David R Sibley; Robert B Innis
Journal:  Neuroimage       Date:  2010-01-22       Impact factor: 6.556

6.  Structure-Functional-Selectivity Relationship Studies of Novel Apomorphine Analogs to Develop D1R/D2R Biased Ligands.

Authors:  Hyejin Park; Aarti N Urs; Joseph Zimmerman; Chuan Liu; Qiu Wang; Nikhil M Urs
Journal:  ACS Med Chem Lett       Date:  2020-01-06       Impact factor: 4.345
  6 in total

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