Literature DB >> 21478838

p38 kinase inhibitor approved for idiopathic pulmonary fibrosis.

Nuala Moran.   

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Year:  2011        PMID： 21478838     DOI： 10.1038/nbt0411-301

Source DB:  PubMed          Journal:  Nat Biotechnol        ISSN： 1087-0156            Impact factor:   54.908


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  1 in total

1.  Bristol-Myers Squibb swallows last of antibody pioneers.

Authors:  Malorye Allison
Journal:  Nat Biotechnol       Date:  2009-09       Impact factor: 54.908
  1 in total
  19 in total

1.  Targeting of Discoidin Domain Receptor 2 (DDR2) Prevents Myofibroblast Activation and Neovessel Formation During Pulmonary Fibrosis.

Authors:  Hu Zhao; Huan Bian; Xin Bu; Shuya Zhang; Pan Zhang; Jiangtian Yu; Xiaofeng Lai; Di Li; Chuchao Zhu; Libo Yao; Jin Su
Journal:  Mol Ther       Date:  2016-05-27       Impact factor: 11.454

2.  The K-Ras effector p38γ MAPK confers intrinsic resistance to tyrosine kinase inhibitors by stimulating EGFR transcription and EGFR dephosphorylation.

Authors:  Ning Yin; Adrienne Lepp; Yongsheng Ji; Matthew Mortensen; Songwang Hou; Xiao-Mei Qi; Charles R Myers; Guan Chen
Journal:  J Biol Chem       Date:  2017-07-24       Impact factor: 5.157

3.  p38γ Mitogen-activated protein kinase signals through phosphorylating its phosphatase PTPH1 in regulating ras protein oncogenesis and stress response.

Authors:  Songwang Hou; Padmanaban S Suresh; Xiaomei Qi; Adrienne Lepp; Shama P Mirza; Guan Chen
Journal:  J Biol Chem       Date:  2012-06-22       Impact factor: 5.157

4.  Role of dual-specificity protein phosphatase DUSP10/MKP-5 in pulmonary fibrosis.

Authors:  Nikos Xylourgidis; Kisuk Min; Farida Ahangari; Guoying Yu; Jose D Herazo-Maya; Theodoros Karampitsakos; Vassilis Aidinis; Leonhard Binzenhöfer; Demosthenes Bouros; Anton M Bennett; Naftali Kaminski; Argyrios Tzouvelekis
Journal:  Am J Physiol Lung Cell Mol Physiol       Date:  2019-09-04       Impact factor: 5.464

5.  p38γ mitogen-activated protein kinase (MAPK) confers breast cancer hormone sensitivity by switching estrogen receptor (ER) signaling from classical to nonclassical pathway via stimulating ER phosphorylation and c-Jun transcription.

Authors:  Xiaomei Qi; Huiying Zhi; Adrienne Lepp; Phillip Wang; Jian Huang; Zainab Basir; Christopher R Chitambar; Charles R Myers; Guan Chen
Journal:  J Biol Chem       Date:  2012-03-07       Impact factor: 5.157

6.  p38γ MAPK is required for inflammation-associated colon tumorigenesis.

Authors:  N Yin; X Qi; S Tsai; Y Lu; Z Basir; K Oshima; J P Thomas; C R Myers; G Stoner; G Chen
Journal:  Oncogene       Date:  2015-05-11       Impact factor: 9.867

7.  p38γ MAPK Is a Therapeutic Target for Triple-Negative Breast Cancer by Stimulation of Cancer Stem-Like Cell Expansion.

Authors:  Xiaomei Qi; Ning Yin; Shao Ma; Adrienne Lepp; Jun Tang; Weiqing Jing; Bryon Johnson; Michael B Dwinell; Christopher R Chitambar; Guan Chen
Journal:  Stem Cells       Date:  2015-06-23       Impact factor: 6.277

8.  Salinomycin and other polyether ionophores are a new class of antiscarring agent.

Authors:  Collynn F Woeller; Charles W O'Loughlin; Elisa Roztocil; Steven E Feldon; Richard P Phipps
Journal:  J Biol Chem       Date:  2014-12-23       Impact factor: 5.157

9.  Inhibition of p38 MAPK attenuates renal atrophy and fibrosis in a murine renal artery stenosis model.

Authors:  Diping Wang; Gina M Warner; Ping Yin; Bruce E Knudsen; Jingfei Cheng; Kim A Butters; Karen R Lien; Catherine E Gray; Vesna D Garovic; Lilach O Lerman; Stephen C Textor; Karl A Nath; Robert D Simari; Joseph P Grande
Journal:  Am J Physiol Renal Physiol       Date:  2013-01-30

Review 10.  Pathophysiological Roles of Stress-Activated Protein Kinases in Pulmonary Fibrosis.

Authors:  Yoshitoshi Kasuya; Jun-Dal Kim; Masahiko Hatano; Koichiro Tatsumi; Shuichi Matsuda
Journal:  Int J Mol Sci       Date:  2021-06-03       Impact factor: 5.923
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