Literature DB >> 21478023

BNCT for locally recurrent head and neck cancer: preliminary clinical experience from a phase I/II trial at Tsing Hua Open-Pool Reactor.

L W Wang1, S J Wang, P Y Chu, C Y Ho, S H Jiang, Y W H Liu, Y H Liu, H M Liu, J J Peir, F I Chou, S H Yen, Y L Lee, C W Chang, C S Liu, Y W Chen, K Ono.   

Abstract

To introduce our preliminary experience of treating locally and regionally recurrent Head and Neck cancer patients at Tsing Hua Open-Pool Reactor in Taiwan, four patients (M/F=3/1, median age 68 Y/O) were enrolled. BNCT with BPA (400 mg/kg) injected in 2 phases and prescription dose of 12-35 Gy (Eq.)/fraction for 2 fractions at 30 day interval can be given with sustained blood boron concentration and tolerable early toxicities for recurrent H & N cancer. Copyright Â
© 2011 Elsevier Ltd. All rights reserved.

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Year:  2011        PMID: 21478023     DOI: 10.1016/j.apradiso.2011.03.008

Source DB:  PubMed          Journal:  Appl Radiat Isot        ISSN: 0969-8043            Impact factor:   1.513


  19 in total

1.  Boron delivery with liposomes for boron neutron capture therapy (BNCT): biodistribution studies in an experimental model of oral cancer demonstrating therapeutic potential.

Authors:  Elisa M Heber; Peter J Kueffer; Mark W Lee; M Frederick Hawthorne; Marcela A Garabalino; Ana J Molinari; David W Nigg; William Bauer; Andrea Monti Hughes; Emiliano C C Pozzi; Verónica A Trivillin; Amanda E Schwint
Journal:  Radiat Environ Biophys       Date:  2012-01-21       Impact factor: 1.925

2.  Nuclear Theranostics in Taiwan.

Authors:  Ko-Han Lin; Yi-Wei Chen; Rheun-Chuan Lee; Ling-Wei Wang; Fong-In Chou; Chi-Wei Chang; Sang-Hue Yen; Wen-Sheng Huang
Journal:  Nucl Med Mol Imaging       Date:  2019-02-01

Review 3.  Advancements in Tumor Targeting Strategies for Boron Neutron Capture Therapy.

Authors:  Micah John Luderer; Pilar de la Puente; Abdel Kareem Azab
Journal:  Pharm Res       Date:  2015-06-02       Impact factor: 4.200

Review 4.  Physical, dosimetric and clinical aspects and delivery systems in neutron capture therapy.

Authors:  Bagher Farhood; Hadi Samadian; Mahdi Ghorbani; Seyed Salman Zakariaee; Courtney Knaup
Journal:  Rep Pract Oncol Radiother       Date:  2018-08-01

5.  Electroporation optimizes the uptake of boron-10 by tumor for boron neutron capture therapy (BNCT) mediated by GB-10: a boron biodistribution study in the hamster cheek pouch oral cancer model.

Authors:  Marcela A Garabalino; Nahuel Olaiz; Agustina Portu; Gisela Saint Martin; Silvia I Thorp; Emiliano C C Pozzi; Paula Curotto; María E Itoiz; Andrea Monti Hughes; Lucas L Colombo; David W Nigg; Verónica A Trivillin; Guillermo Marshall; Amanda E Schwint
Journal:  Radiat Environ Biophys       Date:  2019-05-23       Impact factor: 1.925

Review 6.  Boron neutron capture therapy (BNCT): a unique role in radiotherapy with a view to entering the accelerator-based BNCT era.

Authors:  Minoru Suzuki
Journal:  Int J Clin Oncol       Date:  2019-06-05       Impact factor: 3.402

7.  Boron neutron capture therapy (BNCT) for liver metastasis in an experimental model: dose–response at five-week follow-up based on retrospective dose assessment in individual rats.

Authors:  Emiliano C C Pozzi; Verónica A Trivillin; Lucas L Colombo; Andrea Monti Hughes; Silvia I Thorp; Jorge E Cardoso; Marcela A Garabalino; Ana J Molinari; Elisa M Heber; Paula Curotto; Marcelo Miller; Maria E Itoiz; Romina F Aromando; David W Nigg; Amanda E Schwint
Journal:  Radiat Environ Biophys       Date:  2013-11       Impact factor: 1.925

8.  Boron neutron capture therapy (BNCT) for liver metastasis: therapeutic efficacy in an experimental model.

Authors:  Emiliano C C Pozzi; Jorge E Cardoso; Lucas L Colombo; Silvia Thorp; Andrea Monti Hughes; Ana J Molinari; Marcela A Garabalino; Elisa M Heber; Marcelo Miller; Maria E Itoiz; Romina F Aromando; David W Nigg; Jorge Quintana; Verónica A Trivillin; Amanda E Schwint
Journal:  Radiat Environ Biophys       Date:  2012-04-28       Impact factor: 1.925

9.  Biodistribution of sodium borocaptate (BSH) for boron neutron capture therapy (BNCT) in an oral cancer model.

Authors:  Marcela A Garabalino; Elisa M Heber; Andrea Monti Hughes; Sara J González; Ana J Molinari; Emiliano C C Pozzi; Susana Nievas; Maria E Itoiz; Romina F Aromando; David W Nigg; William Bauer; Verónica A Trivillin; Amanda E Schwint
Journal:  Radiat Environ Biophys       Date:  2013-04-17       Impact factor: 1.925

Review 10.  Boron neutron capture therapy for malignant brain tumors.

Authors:  Shin-Ichi Miyatake; Masahiko Wanibuchi; Naonori Hu; Koji Ono
Journal:  J Neurooncol       Date:  2020-07-16       Impact factor: 4.130

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