Literature DB >> 21477660

Pathophysiological functions of the CagA oncoprotein during infection by Helicobacter pylori.

Naoko Murata-Kamiya1.   

Abstract

Infection with Helicobacter pylori cagA-positive strains plays an essential role in the development of gastric carcinoma. This review summarizes the pathophysiological functions of the cagA gene product, CagA, particularly focusing on the molecular mechanisms underlying CagA translocation into the host cells as well as CagA-mediated deregulation of host cell signaling.
Copyright © 2011 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved.

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Year:  2011        PMID： 21477660     DOI： 10.1016/j.micinf.2011.03.011

Source DB:  PubMed          Journal:  Microbes Infect        ISSN： 1286-4579            Impact factor:   2.700


  25 in total

Review 1.  Gastric microbiome and gastric cancer.

Authors:  Kyle M Brawner; Casey D Morrow; Phillip D Smith
Journal:  Cancer J       Date:  2014 May-Jun       Impact factor: 3.360

2.  Serological response to Helicobacter pylori infection among Latin American populations with contrasting risks of gastric cancer.

Authors:  M Constanza Camargo; Mauricio Beltran; Carlos J Conde-Glez; Paul R Harris; Angelika Michel; Tim Waterboer; Astrid Carolina Flórez; Javier Torres; Catterina Ferreccio; Joshua N Sampson; Michael Pawlita; Charles S Rabkin
Journal:  Int J Cancer       Date:  2015-07-16       Impact factor: 7.396

Review 3.  Life in the human stomach: persistence strategies of the bacterial pathogen Helicobacter pylori.

Authors:  Nina R Salama; Mara L Hartung; Anne Müller
Journal:  Nat Rev Microbiol       Date:  2013-05-08       Impact factor: 60.633

Review 4.  At the Bench: Helicobacter pylori, dysregulated host responses, DNA damage, and gastric cancer.

Authors:  Dana M Hardbower; Richard M Peek; Keith T Wilson
Journal:  J Leukoc Biol       Date:  2014-05-27       Impact factor: 4.962

5.  A novel line immunoassay based on recombinant virulence factors enables highly specific and sensitive serologic diagnosis of Helicobacter pylori infection.

Authors:  Luca Formichella; Laura Romberg; Christian Bolz; Michael Vieth; Michael Geppert; Gereon Göttner; Christina Nölting; Dirk Walter; Wolfgang Schepp; Arne Schneider; Kurt Ulm; Petra Wolf; Dirk H Busch; Erwin Soutschek; Markus Gerhard
Journal:  Clin Vaccine Immunol       Date:  2013-09-04

Review 6.  Relatedness of Helicobacter pylori populations to gastric carcinogenesis.

Authors:  Quan-Jiang Dong; Shu-Hui Zhan; Li-Li Wang; Yong-Ning Xin; Man Jiang; Shi-Ying Xuan
Journal:  World J Gastroenterol       Date:  2012-12-07       Impact factor: 5.742

7.  High Helicobacter pylori Bacterial Load and Low Cytokine Expression Levels Are Associated with Nodular Gastropathy.

Authors:  Rodrigo Mansilla-Vivar; Carolina A Serrano; Camila Palma; Macarena Vera; Caroll Hernandez; Margarita Pizarro; Javiera Torres; Paul R Harris; Eduardo Fuentes-López; Arnoldo Riquelme; Alberto Espino
Journal:  Dig Dis Sci       Date:  2019-08-07       Impact factor: 3.199

Review 8.  Helicobacter and salmonella persistent infection strategies.

Authors:  Denise M Monack
Journal:  Cold Spring Harb Perspect Med       Date:  2013-12-01       Impact factor: 6.915

Review 9.  Association of Helicobacter pylori Infection and Host Cytokine Gene Polymorphism with Gastric Cancer.

Authors:  Md Zeyaullah; Abdullah M AlShahrani; Irfan Ahmad
Journal:  Can J Gastroenterol Hepatol       Date:  2021-05-28

10.  Rho/ROCK-dependent inhibition of 3T3-L1 adipogenesis by G-protein-deamidating dermonecrotic toxins: differential regulation of Notch1, Pref1/Dlk1, and β-catenin signaling.

Authors:  Yuka Bannai; Leila R Aminova; Melinda J Faulkner; Mengfei Ho; Brenda A Wilson
Journal:  Front Cell Infect Microbiol       Date:  2012-06-05       Impact factor: 5.293
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