Literature DB >> 21475751

A single-molecule study of the inhibition effect of Naringenin on transforming growth factor-β ligand-receptor binding.

Yong Yang1, Yongchun Xu, Tie Xia, Fangjin Chen, Chunling Zhang, Wei Liang, Luhua Lai, Xiaohong Fang.   

Abstract

With single-molecule fluorescence imaging and single-molecule force measurement, we have found that the natural compound Naringenin exerts an inhibition effect on TGF-β ligand-receptor interaction, the initial step of TGF-β signaling. © The Royal Society of Chemistry 2011

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Year:  2011        PMID： 21475751     DOI： 10.1039/c1cc10778j

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  7 in total

1.  Naringenin reduces lung metastasis in a breast cancer resection model.

Authors:  Lei Qin; Lingtao Jin; Linlin Lu; Xiaoyan Lu; Chunling Zhang; Fayun Zhang; Wei Liang
Journal:  Protein Cell       Date:  2011-07-12       Impact factor: 14.870

2.  Alleviation of liver cirrhosis and associated portal-hypertension by Astragalus species in relation to their UPLC-MS/MS metabolic profiles: a mechanistic study.

Authors:  Reham S Ibrahim; Nesrine S El-Mezayen; Alaa A El-Banna
Journal:  Sci Rep       Date:  2022-07-13       Impact factor: 4.996

3.  Hesperetin: an inhibitor of the transforming growth factor-β (TGF-β) signaling pathway.

Authors:  Yong Yang; Joy Wolfram; Haifa Shen; Xiaohong Fang; Mauro Ferrari
Journal:  Eur J Med Chem       Date:  2012-10-25       Impact factor: 6.514

4.  Naringenin prevents experimental liver fibrosis by blocking TGFβ-Smad3 and JNK-Smad3 pathways.

Authors:  Erika Hernández-Aquino; Natanael Zarco; Sael Casas-Grajales; Erika Ramos-Tovar; Rosa E Flores-Beltrán; Jonathan Arauz; Mineko Shibayama; Liliana Favari; Víctor Tsutsumi; José Segovia; Pablo Muriel
Journal:  World J Gastroenterol       Date:  2017-06-28       Impact factor: 5.742

5.  Naringenin Modifies the Development of Lineage-Specific Effector CD4+ T Cells.

Authors:  Junpeng Wang; Xinli Niu; Chunfang Wu; Dayong Wu
Journal:  Front Immunol       Date:  2018-10-01       Impact factor: 7.561

6.  Naringenin decreases invasiveness and metastasis by inhibiting TGF-β-induced epithelial to mesenchymal transition in pancreatic cancer cells.

Authors:  Changjie Lou; Fayun Zhang; Ming Yang; Juan Zhao; Wenfeng Zeng; Xiaocui Fang; Yanqiao Zhang; Chunling Zhang; Wei Liang
Journal:  PLoS One       Date:  2012-12-26       Impact factor: 3.240

7.  Naringenin prevents TGF-β1 secretion from breast cancer and suppresses pulmonary metastasis by inhibiting PKC activation.

Authors:  Fayun Zhang; Wenjuan Dong; Wenfeng Zeng; Lei Zhang; Chao Zhang; Yuqi Qiu; Luoyang Wang; Xiaozhe Yin; Chunling Zhang; Wei Liang
Journal:  Breast Cancer Res       Date:  2016-04-01       Impact factor: 6.466
  7 in total

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