Literature DB >> 2147521

Cell cycle control in eukaryotes: molecular mechanisms of cdc2 activation.

G Draetta1.   

Abstract

cdc2 kinase regulates the progression of eukaryotic cells through the division cycle. Events such as cell growth, DNA replication and mitosis are coordinated through the activation of specific forms of this kinase. Here I discuss our present knowledge of the mechanisms that regulate the activity of cdc2 kinase.

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Year:  1990        PMID： 2147521     DOI： 10.1016/0968-0004(90)90235-4

Source DB:  PubMed          Journal:  Trends Biochem Sci        ISSN： 0968-0004            Impact factor:   13.807


  82 in total

1.  Peptides containing cyclin/Cdk-nuclear localization signal motifs derived from viral initiator proteins bind to DNA when unphosphorylated.

Authors:  Ronald J Kim; Stephanie Moine; Danielle K Reese; Peter A Bullock
Journal:  J Virol       Date:  2002-12       Impact factor: 5.103

2.  Transforming growth factor beta 1 (TGF beta 1) reduces cellular levels of p34cdc2, and this effect is abrogated by adenovirus independently of the E1A-associated pRB binding activity.

Authors:  S E Abraham; M C Carter; E Moran
Journal:  Mol Biol Cell       Date:  1992-06       Impact factor: 4.138

3.  Nucleotide sequence of a rabbit cDNA encoding elongation factor 1 gamma.

Authors:  G T Sheu; J A Traugh
Journal:  Nucleic Acids Res       Date:  1992-11-11       Impact factor: 16.971

4.  Analysis of wild-type and mutant p21WAF-1 gene activities.

Authors:  J Lin; C Reichner; X Wu; A J Levine
Journal:  Mol Cell Biol       Date:  1996-04       Impact factor: 4.272

5.  The c-mos gene product is required for cyclin B accumulation during meiosis of mouse eggs.

Authors:  S J O'Keefe; A A Kiessling; G M Cooper
Journal:  Proc Natl Acad Sci U S A       Date:  1991-09-01       Impact factor: 11.205

6.  A minimal cascade model for the mitotic oscillator involving cyclin and cdc2 kinase.

Authors:  A Goldbeter
Journal:  Proc Natl Acad Sci U S A       Date:  1991-10-15       Impact factor: 11.205

7.  cDNA cloning of the HMGI-C phosphoprotein, a nuclear protein associated with neoplastic and undifferentiated phenotypes.

Authors:  G Manfioletti; V Giancotti; A Bandiera; E Buratti; P Sautière; P Cary; C Crane-Robinson; B Coles; G H Goodwin
Journal:  Nucleic Acids Res       Date:  1991-12-25       Impact factor: 16.971

8.  A novel nuclear inhibitor I-92 regulates DNA binding activity of octamer binding protein p92 during the cell cycle.

Authors:  J Weitz; M Kopun; M Stoehr; I Napierski; H D Royer
Journal:  Nucleic Acids Res       Date:  1991-10-25       Impact factor: 16.971

9.  SNT, a differentiation-specific target of neurotrophic factor-induced tyrosine kinase activity in neurons and PC12 cells.

Authors:  S J Rabin; V Cleghon; D R Kaplan
Journal:  Mol Cell Biol       Date:  1993-04       Impact factor: 4.272

10.  Understanding and modulating cyclin-dependent kinase inhibitor specificity: molecular modeling and biochemical evaluation of pyrazolopyrimidinones as CDK2/cyclin A and CDK4/cyclin D1 inhibitors.

Authors:  Karen A Rossi; Jay A Markwalder; Steven P Seitz; Chong-Hwan Chang; Sarah Cox; Michael D Boisclair; Leonardo Brizuela; Stephen L Brenner; Pieter F W Stouten
Journal:  J Comput Aided Mol Des       Date:  2005-02       Impact factor: 3.686
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