Literature DB >> 21472180

N-heterocyclic carbene-catalyzed [4 + 1] annulation of phthalaldehyde and imines.

Fang-gang Sun1, Song Ye.   

Abstract

The diastereoselective synthesis of cis-2-amino-3-hydroxyindanones was realized by the N-heterocyclic carbene-catalyzed [4 + 1] annulation of phthalaldehyde and imines, which may involve a tandem aza-benzoin reaction and aldol reaction.

Entities:  

Year:  2011        PMID: 21472180     DOI: 10.1039/c1ob05092c

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN: 1477-0520            Impact factor:   3.876


  1 in total

Review 1.  Recent advances in N-heterocyclic carbene (NHC)-catalysed benzoin reactions.

Authors:  Rajeev S Menon; Akkattu T Biju; Vijay Nair
Journal:  Beilstein J Org Chem       Date:  2016-03-09       Impact factor: 2.883

  1 in total

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