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Literature DB >> 21472175

Muscarine, imidazole, oxazole, and thiazole alkaloids.

Abstract

A great number of structurally diverse natural products containing five-membered heterocyclic subunits, such as imidazole, oxazole, thiazole, and their saturated congeners, are abundant in nature. These naturally occurring metabolites often exhibit extensive and pharmacologically important biological activities. The latest progress in the isolation, biological activities, chemical synthetic studies, and biosynthetic pathways on these natural products is summarized in this review.

Entities: Chemical

Mesh：

Substances：

Year: 2011 PMID： 21472175 DOI： 10.1039/c0np00074d

Source DB: PubMed Journal: Nat Prod Rep ISSN： 0265-0568 Impact factor: 13.423

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Cited

23 in total

1. Total synthesis of 7'-desmethylkealiiquinone.

Authors: Heather M Lima; Rasapalli Sivappa; Muhammed Yousufuddin; Carl J Lovely
Journal: Org Lett Date: 2012-04-24 Impact factor: 6.005

Review 2. Heteroatom-Heteroatom Bond Formation in Natural Product Biosynthesis.

Authors: Abraham J Waldman; Tai L Ng; Peng Wang; Emily P Balskus
Journal: Chem Rev Date: 2017-04-04 Impact factor: 60.622

3. Getting the Right Grip? How Understanding Electrophile Selectivity Profiles Could Illuminate Our Understanding of Redox Signaling.

Authors: Marcus J C Long; Lingxi Wang; Yimon Aye
Journal: Antioxid Redox Signal Date: 2019-11-04 Impact factor: 8.401

Review 4. Applications of Friedel-Crafts reactions in total synthesis of natural products.

Authors: Majid M Heravi; Vahideh Zadsirjan; Pegah Saedi; Tayebeh Momeni
Journal: RSC Adv Date: 2018-12-03 Impact factor: 4.036

5. Total syntheses of kealiinines A-C.

Authors: Jayanta Das; Panduka B Koswatta; J Daniel Jones; Muhammed Yousufuddin; Carl J Lovely
Journal: Org Lett Date: 2012-12-05 Impact factor: 6.005

6. Room temperature copper(II)-catalyzed oxidative cyclization of enamides to 2,5-disubstituted oxazoles via vinylic C-H functionalization.

Authors: Chi Wai Cheung; Stephen L Buchwald
Journal: J Org Chem Date: 2012-08-13 Impact factor: 4.354

Muscarine, imidazole, oxazole, and thiazole alkaloids.

1. Total synthesis of 7'-desmethylkealiiquinone.

Review 2. Heteroatom-Heteroatom Bond Formation in Natural Product Biosynthesis.

3. Getting the Right Grip? How Understanding Electrophile Selectivity Profiles Could Illuminate Our Understanding of Redox Signaling.

Review 4. Applications of Friedel-Crafts reactions in total synthesis of natural products.

5. Total syntheses of kealiinines A-C.

6. Room temperature copper(II)-catalyzed oxidative cyclization of enamides to 2,5-disubstituted oxazoles via vinylic C-H functionalization.

7. Room-temperature palladium-catalyzed direct 2-arylation of benzoxazoles with aryl and heteroaryl bromides.

Review 8. Imidazoles as potential anticancer agents.

Review 9. Mechanisms of cyanobactin biosynthesis.

10. Thiazole-amino acids: influence of thiazole ring on conformational properties of amino acid residues.