Literature DB >> 21471246

Common HIV-1 peptide variants mediate differential binding of KIR3DL1 to HLA-Bw4 molecules.

Lena Fadda1, Geraldine M O'Connor, Swati Kumar, Alicja Piechocka-Trocha, Clair M Gardiner, Mary Carrington, Daniel W McVicar, Marcus Altfeld.   

Abstract

Epidemiological studies have shown the protective effect of KIR3DL1/HLA-Bw4 genotypes in human immunodeficiency virus type 1 (HIV-1) infection; however, the functional correlates for the protective effect remain unknown. We investigated whether human leukocyte antigen (HLA)-Bw4-presented HIV-1 peptides could affect the interaction between the inhibitory natural killer (NK) cell receptor KIR3DL1 and its ligand HLA-Bw4. Distinct HIV-1 epitopes differentially modulated the binding of KIR3DL1 to HLA-Bw4. Furthermore, cytotoxic T lymphocyte (CTL) escape mutations within the immunodominant HLA-B57 (Bw4)-restricted Gag epitope TSTLQEQIGW abrogated KIR3DL1 binding to HLA-B57, suggesting that sensing of CTL escape variants by NK cells can contribute to the protective effect of the KIR3DL1/HLA-Bw4 compound genotype.

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Year:  2011        PMID： 21471246      PMCID： PMC3126328          DOI： 10.1128/JVI.00412-11

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  17 in total

1.  Crystal structure of an NK cell immunoglobulin-like receptor in complex with its class I MHC ligand.

Authors:  J C Boyington; S A Motyka; P Schuck; A G Brooks; P D Sun
Journal:  Nature       Date:  2000-06-01       Impact factor: 49.962

2.  Functional polymorphism of the KIR3DL1/S1 receptor on human NK cells.

Authors:  Geraldine M O'Connor; Kieran J Guinan; Rodat T Cunningham; Derek Middleton; Peter Parham; Clair M Gardiner
Journal:  J Immunol       Date:  2007-01-01       Impact factor: 5.422

3.  Peptide sequence requirements for the recognition of HLA-B*2705 by specific natural killer cells.

Authors:  M Peruzzi; K C Parker; E O Long; M S Malnati
Journal:  J Immunol       Date:  1996-10-15       Impact factor: 5.422

4.  Innate partnership of HLA-B and KIR3DL1 subtypes against HIV-1.

Authors:  Maureen P Martin; Ying Qi; Xiaojiang Gao; Eriko Yamada; Jeffrey N Martin; Florencia Pereyra; Sara Colombo; Elizabeth E Brown; W Lesley Shupert; John Phair; James J Goedert; Susan Buchbinder; Gregory D Kirk; Amalio Telenti; Mark Connors; Stephen J O'Brien; Bruce D Walker; Peter Parham; Steven G Deeks; Daniel W McVicar; Mary Carrington
Journal:  Nat Genet       Date:  2007-05-13       Impact factor: 38.330

5.  Epistatic interaction between KIR3DS1 and HLA-B delays the progression to AIDS.

Authors:  Maureen P Martin; Xiaojiang Gao; Jeong-Hee Lee; George W Nelson; Roger Detels; James J Goedert; Susan Buchbinder; Keith Hoots; David Vlahov; John Trowsdale; Michael Wilson; Stephen J O'Brien; Mary Carrington
Journal:  Nat Genet       Date:  2002-07-22       Impact factor: 38.330

6.  Escape and compensation from early HLA-B57-mediated cytotoxic T-lymphocyte pressure on human immunodeficiency virus type 1 Gag alter capsid interactions with cyclophilin A.

Authors:  Mark A Brockman; Arne Schneidewind; Matthew Lahaie; Aaron Schmidt; Toshiyuki Miura; Ivna Desouza; Faina Ryvkin; Cynthia A Derdeyn; Susan Allen; Eric Hunter; Joseph Mulenga; Paul A Goepfert; Bruce D Walker; Todd M Allen
Journal:  J Virol       Date:  2007-08-29       Impact factor: 5.103

7.  HIV evolution: CTL escape mutation and reversion after transmission.

Authors:  A J Leslie; K J Pfafferott; P Chetty; R Draenert; M M Addo; M Feeney; Y Tang; E C Holmes; T Allen; J G Prado; M Altfeld; C Brander; C Dixon; D Ramduth; P Jeena; S A Thomas; A St John; T A Roach; B Kupfer; G Luzzi; A Edwards; G Taylor; H Lyall; G Tudor-Williams; V Novelli; J Martinez-Picado; P Kiepiela; B D Walker; P J R Goulder
Journal:  Nat Med       Date:  2004-02-08       Impact factor: 53.440

Review 8.  The influence of HLA genotype on AIDS.

Authors:  Mary Carrington; Stephen J O'Brien
Journal:  Annu Rev Med       Date:  2001-12-03       Impact factor: 13.739

9.  An early HIV mutation within an HLA-B*57-restricted T cell epitope abrogates binding to the killer inhibitory receptor 3DL1.

Authors:  Simon Brackenridge; Edward J Evans; Mireille Toebes; Nilu Goonetilleke; Michael K P Liu; Kati di Gleria; Ton N Schumacher; Simon J Davis; Andrew J McMichael; Geraldine M Gillespie
Journal:  J Virol       Date:  2011-03-23       Impact factor: 5.103

10.  Cutting Edge: Allele-specific and peptide-dependent interactions between KIR3DL1 and HLA-A and HLA-B.

Authors:  Hathairat Thananchai; Geraldine Gillespie; Maureen P Martin; Arman Bashirova; Nobuyo Yawata; Makoto Yawata; Philippa Easterbrook; Daniel W McVicar; Katsumi Maenaka; Peter Parham; Mary Carrington; Tao Dong; Sarah Rowland-Jones
Journal:  J Immunol       Date:  2007-01-01       Impact factor: 5.422
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  46 in total

1.  Impact of protective killer inhibitory receptor/human leukocyte antigen genotypes on natural killer cell and T-cell function in HIV-1-infected controllers.

Authors:  Costin Tomescu; Fuh-Mei Duh; Rebecca Hoh; Anne Viviani; Kara Harvill; Maureen P Martin; Mary Carrington; Steven G Deeks; Luis J Montaner
Journal:  AIDS       Date:  2012-09-24       Impact factor: 4.177

2.  Novel HIV vaccine strategies: overview and perspective.

Authors:  Yehuda Z Cohen; Raphael Dolin
Journal:  Ther Adv Vaccines       Date:  2013-09

3.  HIV-1-Mediated Downmodulation of HLA-C Impacts Target Cell Recognition and Antiviral Activity of NK Cells.

Authors:  Christian Körner; Camille R Simoneau; Philipp Schommers; Mitchell Granoff; Maja Ziegler; Angelique Hölzemer; Sebastian Lunemann; Janet Chukwukelu; Björn Corleis; Vivek Naranbhai; Douglas S Kwon; Eileen P Scully; Stephanie Jost; Frank Kirchhoff; Mary Carrington; Marcus Altfeld
Journal:  Cell Host Microbe       Date:  2017-07-12       Impact factor: 21.023

Review 4.  Evasion from NK cell-mediated immune responses by HIV-1.

Authors:  Stephanie Jost; Marcus Altfeld
Journal:  Microbes Infect       Date:  2012-05-21       Impact factor: 2.700

5.  Behçet disease-associated MHC class I residues implicate antigen binding and regulation of cell-mediated cytotoxicity.

Authors:  Michael J Ombrello; Yohei Kirino; Paul I W de Bakker; Ahmet Gül; Daniel L Kastner; Elaine F Remmers
Journal:  Proc Natl Acad Sci U S A       Date:  2014-05-12       Impact factor: 11.205

6.  MHC-I peptides get out of the groove and enable a novel mechanism of HIV-1 escape.

Authors:  Phillip Pymm; Patricia T Illing; Sri H Ramarathinam; Geraldine M O'Connor; Victoria A Hughes; Corinne Hitchen; David A Price; Bosco K Ho; Daniel W McVicar; Andrew G Brooks; Anthony W Purcell; Jamie Rossjohn; Julian P Vivian
Journal:  Nat Struct Mol Biol       Date:  2017-02-20       Impact factor: 15.369

Review 7.  Defining the role of NK cells during dengue virus infection.

Authors:  Anuja Mathew
Journal:  Immunology       Date:  2018-03-23       Impact factor: 7.397

Review 8.  Natural Killer Cell Education and the Response to Infection and Cancer Therapy: Stay Tuned.

Authors:  Jeanette E Boudreau; Katharine C Hsu
Journal:  Trends Immunol       Date:  2018-01-31       Impact factor: 16.687

Review 9.  Structural insights into activation of antiviral NK cell responses.

Authors:  Kathryn A Finton; Roland K Strong
Journal:  Immunol Rev       Date:  2012-11       Impact factor: 12.988

10.  Degenerate recognition of MHC class I molecules with Bw4 and Bw6 motifs by a killer cell Ig-like receptor 3DL expressed by macaque NK cells.

Authors:  Sebastien M Maloveste; Dan Chen; Emma Gostick; Julian P Vivian; Ronald J Plishka; Ranjini Iyengar; Robin L Kruthers; Alicia Buckler-White; Andrew G Brooks; Jamie Rossjohn; David A Price; Bernard A P Lafont
Journal:  J Immunol       Date:  2012-10-05       Impact factor: 5.422
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