| Literature DB >> 21469662 |
Roberto Fernández de la Pradilla1, Ignacio Colomer, Mercedes Ureña, Alma Viso.
Abstract
Treatment of acyclic α-hydroxy and α-tosylamino sulfinyl dienes with amines affords enantiopure 1,4-diol or 1,4-hydroxysulfonamide derivatives in good yields and diastereoselectivities. This one-pot procedure entails a conjugate addition that triggers a diastereoselective sulfoxide-sulfenate [2,3]-sigmatropic rearrangement.Entities:
Mesh：
Substances：
Year: 2011 PMID： 21469662 DOI： 10.1021/ol200718y
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005