| Literature DB >> 21468223 |
Abstract
Intestinal dendritic cells (DC) and macrophages play a key role for the maintenance of intestinal integrity by initiating innate and adaptive immune responses. Although DC and macrophages have been viewed as distinct lineages, the reliability of surface markers for the definition of DC and macrophages has recently been questioned. Here, I will discuss the ontogeny and function of CX(3)CR1(+) mononuclear cells in the small and large intestine.Entities:
Keywords: CX3CR1; commensal microbiota; dendritic cells; gut immunology; macrophages
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Year: 2010 PMID: 21468223 PMCID: PMC3056106 DOI: 10.4161/gmic.1.6.13939
Source DB: PubMed Journal: Gut Microbes ISSN: 1949-0976