Literature DB >> 21464062

Interleukin-6 in surgery, trauma, and critical care part II: clinical implications.

Randeep S Jawa1, Sergio Anillo, Kristin Huntoon, Heinz Baumann, Mahmoud Kulaylat.   

Abstract

A variety of cytokines play a role in the inflammatory response. Interleukin-6 (IL-6)-type cytokines are released in response to tissue injury or an inflammatory stimulus, and act locally and systemically to generate a variety of physiologic responses. Interleukin-6 concentrations are elevated after surgery, trauma, and critical illness. The magnitude of IL-6 elevation correlates with the extent of tissue trauma/injury severity. Furthermore, there is an association between IL-6 elevation and adverse outcome. Interleukin-6 levels can also be used to stratify patients for therapeutic intervention.

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Year:  2011        PMID： 21464062      PMCID： PMC6223019          DOI： 10.1177/0885066610384188

Source DB:  PubMed          Journal:  J Intensive Care Med        ISSN： 0885-0666            Impact factor:   3.510


  81 in total

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2.  Cross-talk among gp130 cytokines in adipocytes.

Authors:  Sanjin Zvonic; James E Baugh; Patricia Arbour-Reily; Randall L Mynatt; Jacqueline M Stephens
Journal:  J Biol Chem       Date:  2005-08-11       Impact factor: 5.157

3.  Interleukin-6, interleukin-8, and a rapid and sensitive assay for calcitonin precursors for the determination of bacterial sepsis in febrile neutropenic children.

Authors:  Glenn R Stryjewski; Eric S Nylen; Michael J Bell; Richard H Snider; Kenneth L Becker; Amy Wu; Christopher Lawlor; Heidi Dalton
Journal:  Pediatr Crit Care Med       Date:  2005-03       Impact factor: 3.624

4.  Effect of mechanical ventilation on inflammatory mediators in patients with acute respiratory distress syndrome: a randomized controlled trial.

Authors:  V M Ranieri; P M Suter; C Tortorella; R De Tullio; J M Dayer; A Brienza; F Bruno; A S Slutsky
Journal:  JAMA       Date:  1999-07-07       Impact factor: 56.272

5.  Circulating soluble gp130, soluble IL-6R, and IL-6 in patients undergoing cardiac surgery, with or without extracorporeal circulation.

Authors:  P Corbi; M Rahmati; A Delwail; D Potreau; P Menu; J Wijdenes; J C Lecron
Journal:  Eur J Cardiothorac Surg       Date:  2000-07       Impact factor: 4.191

6.  Postmortem cytokine levels and severity of traumatic injuries.

Authors:  Sohtaro Mimasaka; Yuki Ohtsu; Shigeyuki Tsunenari; Masato Funayama
Journal:  Int J Legal Med       Date:  2006-04-04       Impact factor: 2.686

7.  Effect of interleukin-6 blockade on tissue factor-induced coagulation in human endotoxemia.

Authors:  Ulla Derhaschnig; Doris Bergmair; Claudia Marsik; Irene Schlifke; John Wijdenes; Bernd Jilma
Journal:  Crit Care Med       Date:  2004-05       Impact factor: 7.598

8.  Interleukin-6 (IL-6) and tumour necrosis factor-alpha in open and laparoscopic cholecystectomy.

Authors:  Z Haq; M Rahman; M A Siddique; R K Roy; A M Rahman; M Khatun
Journal:  Mymensingh Med J       Date:  2004-07

9.  Intracerebral hemorrhage triggers interleukin-6 and interleukin-10 release in blood.

Authors:  Tomasz Dziedzic; Stanislaw Bartus; Aleksandra Klimkowicz; Maciej Motyl; Agnieszka Slowik; Andrzej Szczudlik
Journal:  Stroke       Date:  2002-09       Impact factor: 7.914

Review 10.  Chemokines in acute respiratory distress syndrome.

Authors:  Padmam Puneet; Shabbir Moochhala; Madhav Bhatia
Journal:  Am J Physiol Lung Cell Mol Physiol       Date:  2005-01       Impact factor: 5.464
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  56 in total

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Authors:  Amália M Bielemann; Raissa M Marcello-Machado; Fábio Renato Manzolli Leite; Frederico Canato Martinho; Otacílio Luiz Chagas-Júnior; Altair Antoninha Del Bel Cury; Fernanda Faot
Journal:  Clin Oral Investig       Date:  2017-07-14       Impact factor: 3.573

2.  Clinical relevance of IL-6 gene polymorphism in severely injured patients.

Authors:  Vasilije Jeremić; Tamara Alempijević; Srđan Mijatović; Ana Sijački; Sanja Dragašević; Sonja Pavlović; Biljana Miličić; Slobodan Krstić
Journal:  Bosn J Basic Med Sci       Date:  2014-05       Impact factor: 3.363

3.  Impact of Injury Severity on Dynamic Inflammation Networks Following Blunt Trauma.

Authors:  Khalid Almahmoud; Rami A Namas; Othman Abdul-Malak; Akram M Zaaqoq; Ruben Zamora; Brian S Zuckerbraun; Jason Sperry; Andrew B Peitzman; Timothy R Billiar; Yoram Vodovotz
Journal:  Shock       Date:  2015-08       Impact factor: 3.454

Review 4.  Using IL-6 concentrations in the first 24 h following trauma to predict immunological complications and mortality in trauma patients: a meta-analysis.

Authors:  Zhi Qiao; Weikang Wang; Luxu Yin; Peng Luo; Johannes Greven; Klemens Horst; Frank Hildebrand
Journal:  Eur J Trauma Emerg Surg       Date:  2017-11-14       Impact factor: 3.693

5.  Identification of Plasma Proteome Signatures Associated With Surgery Using SOMAscan.

Authors:  Tamara G Fong; Noel Y Chan; Simon T Dillon; Wenxiao Zhou; Bridget Tripp; Long H Ngo; Hasan H Otu; Sharon K Inouye; Sarinnapha M Vasunilashorn; Zara Cooper; Zhongcong Xie; Edward R Marcantonio; Towia A Libermann
Journal:  Ann Surg       Date:  2021-04-01       Impact factor: 12.969

6.  Effect of Preoperative Administration of Oral Arginine and Glutamine in Patients with Enterocutaneous Fistula Submitted to Definitive Surgery: a Prospective Randomized Trial.

Authors:  Jose L Martinez; Ilka Bosco-Garate; Luis Manuel Souza-Gallardo; José D Méndez; Marco A Juárez-Oropeza; Ruben Román-Ramos; Eduardo Ferat-Osorio
Journal:  J Gastrointest Surg       Date:  2019-02-01       Impact factor: 3.452

7.  Blocking CXCL1-dependent neutrophil recruitment prevents immune damage and reduces pulmonary bacterial infection after inhalation injury.

Authors:  Julia L M Dunn; Laurel B Kartchner; Wesley H Stepp; Lindsey I Glenn; Madison M Malfitano; Samuel W Jones; Claire M Doerschuk; Robert Maile; Bruce A Cairns
Journal:  Am J Physiol Lung Cell Mol Physiol       Date:  2018-01-25       Impact factor: 5.464

Review 8.  Inflammatory response to trauma: implications for coagulation and resuscitation.

Authors:  Albert Pierce; Jean-François Pittet
Journal:  Curr Opin Anaesthesiol       Date:  2014-04       Impact factor: 2.706

9.  Plasma Concentrations of Soluble Suppression of Tumorigenicity-2 and Interleukin-6 Are Predictive of Successful Liberation From Mechanical Ventilation in Patients With the Acute Respiratory Distress Syndrome.

Authors:  Jehan W Alladina; Sean D Levy; Kathryn A Hibbert; James L Januzzi; R Scott Harris; Michael A Matthay; B Taylor Thompson; Ednan K Bajwa
Journal:  Crit Care Med       Date:  2016-09       Impact factor: 7.598

10.  Hemorrhagic shock and resuscitation are associated with peripheral blood mononuclear cell mitochondrial dysfunction and immunosuppression.

Authors:  Jose Paul Perales Villarroel; Yuxia Guan; Evan Werlin; Mary A Selak; Lance B Becker; Carrie A Sims
Journal:  J Trauma Acute Care Surg       Date:  2013-07       Impact factor: 3.313
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