Literature DB >> 21463945

Experimental verification of beam characteristics for cyclotron-based epithermal neutron source (C-BENS).

H Tanaka1, Y Sakurai, M Suzuki, S Masunaga, T Mitsumoto, K Fujita, G Kashino, Y Kinashi, Y Liu, M Takada, K Ono, A Maruhashi.   

Abstract

A cyclotron-based epithermal neutron source has been developed for boron neutron capture therapy. This system consists of a cyclotron accelerator producing 1.1-mA proton beams with an energy of 30 MeV, a beam transport system coupled with a beryllium neutron production target, and a beam-shaping assembly (BSA) with a neutron collimator. In our previous work, the BSA was optimized to obtain sufficient epithermal neutron fluxes of ~10(9) cm(-2) s(-1) using a Monte Carlo simulation code. In order to validate the simulation results, irradiation tests using multi-foil activation at the surface of a gamma-ray shield located behind the collimator and water phantom experiments using a collimated epithermal neutron beam were performed. It was confirmed experimentally that the intensity of the epithermal neutrons was 1.2×10(9) cm(-2) s(-1). Copyright Â
© 2011 Elsevier Ltd. All rights reserved.

Entities:  

Year:  2011        PMID: 21463945     DOI: 10.1016/j.apradiso.2011.03.020

Source DB:  PubMed          Journal:  Appl Radiat Isot        ISSN: 0969-8043            Impact factor:   1.513


  18 in total

1.  Determination of the thermal and epithermal neutron sensitivities of an LBO chamber.

Authors:  Satoru Endo; Hitoshi Sato; Takuto Shimazaki; Erika Nakajima; Kei Kotani; Mitsuru Suda; Tsuyoshi Hamano; Tsuyoshi Kajimoto; Kenichi Tanaka; Masaharu Hoshi
Journal:  Radiat Environ Biophys       Date:  2017-06-21       Impact factor: 1.925

Review 2.  Physical, dosimetric and clinical aspects and delivery systems in neutron capture therapy.

Authors:  Bagher Farhood; Hadi Samadian; Mahdi Ghorbani; Seyed Salman Zakariaee; Courtney Knaup
Journal:  Rep Pract Oncol Radiother       Date:  2018-08-01

3.  Present status of Accelerator-Based BNCT.

Authors:  Andres Juan Kreiner; Javier Bergueiro; Daniel Cartelli; Matias Baldo; Walter Castell; Javier Gomez Asoia; Javier Padulo; Juan Carlos Suárez Sandín; Marcelo Igarzabal; Julian Erhardt; Daniel Mercuri; Alejandro A Valda; Daniel M Minsky; Mario E Debray; Hector R Somacal; María Eugenia Capoulat; María S Herrera; Mariela F Del Grosso; Leonardo Gagetti; Manuel Suarez Anzorena; Nicolas Canepa; Nicolas Real; Marcelo Gun; Hernán Tacca
Journal:  Rep Pract Oncol Radiother       Date:  2014-12-12

Review 4.  Physics of epi-thermal boron neutron capture therapy (epi-thermal BNCT).

Authors:  Ryoichi Seki; Yushi Wakisaka; Nami Morimoto; Masaaki Takashina; Masahiko Koizumi; Hiroshi Toki; Mitsuhiro Fukuda
Journal:  Radiol Phys Technol       Date:  2017-11-20

Review 5.  Boron neutron capture therapy (BNCT): a unique role in radiotherapy with a view to entering the accelerator-based BNCT era.

Authors:  Minoru Suzuki
Journal:  Int J Clin Oncol       Date:  2019-06-05       Impact factor: 3.402

6.  Determining a methodology of dosimetric quality assurance for commercially available accelerator-based boron neutron capture therapy system.

Authors:  Katsumi Hirose; Takahiro Kato; Takaomi Harada; Tomoaki Motoyanagi; Hiroki Tanaka; Akihiko Takeuchi; Ryohei Kato; Shinya Komori; Yuhei Yamazaki; Kazuhiro Arai; Noriyuki Kadoya; Mariko Sato; Yoshihiro Takai
Journal:  J Radiat Res       Date:  2022-07-19       Impact factor: 2.438

7.  Evaluation of radioactivity in the bodies of mice induced by neutron exposure from an epi-thermal neutron source of an accelerator-based boron neutron capture therapy system.

Authors:  Satoshi Nakamura; Shoji Imamichi; Kazuyoshi Masumoto; Masashi Ito; Akihisa Wakita; Hiroyuki Okamoto; Shie Nishioka; Kotaro Iijima; Kazuma Kobayashi; Yoshihisa Abe; Hiroshi Igaki; Kazuyoshi Kurita; Teiji Nishio; Mitsuko Masutani; Jun Itami
Journal:  Proc Jpn Acad Ser B Phys Biol Sci       Date:  2017       Impact factor: 3.493

8.  Accelerator-based BNCT for patients with recurrent glioblastoma: a multicenter phase II study.

Authors:  Shinji Kawabata; Minoru Suzuki; Katsumi Hirose; Hiroki Tanaka; Takahiro Kato; Hiromi Goto; Yoshitaka Narita; Shin-Ichi Miyatake
Journal:  Neurooncol Adv       Date:  2021-05-20

Review 9.  Current status of boron neutron capture therapy of high grade gliomas and recurrent head and neck cancer.

Authors:  Rolf F Barth; M Graca H Vicente; Otto K Harling; W S Kiger; Kent J Riley; Peter J Binns; Franz M Wagner; Minoru Suzuki; Teruhito Aihara; Itsuro Kato; Shinji Kawabata
Journal:  Radiat Oncol       Date:  2012-08-29       Impact factor: 3.481

Review 10.  Boron Neutron Capture Therapy for Malignant Brain Tumors.

Authors:  Shin-Ichi Miyatake; Shinji Kawabata; Ryo Hiramatsu; Toshihiko Kuroiwa; Minoru Suzuki; Natsuko Kondo; Koji Ono
Journal:  Neurol Med Chir (Tokyo)       Date:  2016-05-31       Impact factor: 1.742

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