Literature DB >> 2146361

CD4+ cytolytic T cell clone confers protection against murine malaria.

M Tsuji1, P Romero, R S Nussenzweig, F Zavala.   

Abstract

A CD4+ T cell clone (A1.6) was derived from spleen cells of mice immunized with irradiated sporozoites. This T cell clone recognizes an antigen that is shared by sporozoites and blood forms of Plasmodium berghei and differs from the circumsporozoite protein. Clone A1.6 displays cytotoxic activity, produces IFN-gamma and IL-2 in vitro, and recognizes the plasmodial antigen in the context of the class II I-Ed molecule. Passive transfer of this CD4+ clone into naive mice resulted in a high degree of protection against sporozoite challenge.

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Year:  1990        PMID： 2146361      PMCID： PMC2188671          DOI： 10.1084/jem.172.5.1353

Source DB:  PubMed          Journal:  J Exp Med        ISSN： 0022-1007            Impact factor:   14.307


  10 in total

Review 1.  Rationale for the development of an engineered sporozoite malaria vaccine.

Authors:  V Nussenzweig; R S Nussenzweig
Journal:  Adv Immunol       Date:  1989       Impact factor: 3.543

2.  Low doses of interleukin 2 induce bystander cell lysis by antigen-specific CD4+ inflammatory T cell clones in short-term assay.

Authors:  S H Gromkowski; K M Hepler; C A Janeway
Journal:  Eur J Immunol       Date:  1988-09       Impact factor: 5.532

3.  CD8+ T cells (cytotoxic/suppressors) are required for protection in mice immunized with malaria sporozoites.

Authors:  W R Weiss; M Sedegah; R L Beaudoin; L H Miller; M F Good
Journal:  Proc Natl Acad Sci U S A       Date:  1988-01       Impact factor: 11.205

4.  Inhibition of development of exoerythrocytic forms of malaria parasites by gamma-interferon.

Authors:  A Ferreira; L Schofield; V Enea; H Schellekens; P van der Meide; W E Collins; R S Nussenzweig; V Nussenzweig
Journal:  Science       Date:  1986-05-16       Impact factor: 47.728

5.  Protective immunity produced by the injection of x-irradiated sporozoites of Plasmodium berghei. II. Effects of radiation on sporozoites.

Authors:  J P Vanderberg; R S Nussenzweig; H Most; C G Orton
Journal:  J Parasitol       Date:  1968-12       Impact factor: 1.276

6.  Gamma interferon, CD8+ T cells and antibodies required for immunity to malaria sporozoites.

Authors:  L Schofield; J Villaquiran; A Ferreira; H Schellekens; R Nussenzweig; V Nussenzweig
Journal:  Nature       Date:  1987 Dec 17-23       Impact factor: 49.962

7.  Inhibition of murine malaria (Plasmodium chabaudi) in vivo by recombinant interferon-gamma or tumor necrosis factor, and its enhancement by butylated hydroxyanisole.

Authors:  I A Clark; N H Hunt; G A Butcher; W B Cowden
Journal:  J Immunol       Date:  1987-11-15       Impact factor: 5.422

8.  Role of IFN-gamma in lethal and nonlethal malaria in susceptible and resistant murine hosts.

Authors:  H L Shear; R Srinivasan; T Nolan; C Ng
Journal:  J Immunol       Date:  1989-09-15       Impact factor: 5.422

9.  Shared idiotopes between anti-class II monoclonal antibodies and major histocompatibility complex recognition site of T cells.

Authors:  M Tsuji; J Yagi; R Abe; Y Asano; T Tada
Journal:  Eur J Immunol       Date:  1987-05       Impact factor: 5.532

10.  Expression of class I and class II major histocompatibility complex antigens on human hepatocytes.

Authors:  A Franco; V Barnaba; P Natali; C Balsano; A Musca; F Balsano
Journal:  Hepatology       Date:  1988 May-Jun       Impact factor: 17.425
  10 in total
  47 in total

Review 1.  Parasite heat-shock proteins and host responses: the balance between protection and immunopathology.

Authors:  D Mazier; D Mattei
Journal:  Springer Semin Immunopathol       Date:  1991

Review 2.  Looking under the skin: the first steps in malarial infection and immunity.

Authors:  Robert Ménard; Joana Tavares; Ian Cockburn; Miles Markus; Fidel Zavala; Rogerio Amino
Journal:  Nat Rev Microbiol       Date:  2013-10       Impact factor: 60.633

3.  A potent malaria vaccine based on adenovirus with dual modifications at Hexon and pVII.

Authors:  Takayuki Shiratsuchi; Urvashi Rai; Izumi Kaneko; Min Zhang; Shiroh Iwanaga; Masao Yuda; Moriya Tsuji
Journal:  Vaccine       Date:  2017-10-28       Impact factor: 3.641

4.  A Recombinant Chimeric Ad5/3 Vector Expressing a Multistage Plasmodium Antigen Induces Protective Immunity in Mice Using Heterologous Prime-Boost Immunization Regimens.

Authors:  Monica Cabrera-Mora; Jairo Andres Fonseca; Balwan Singh; Chunxia Zhao; Natalia Makarova; Igor Dmitriev; David T Curiel; Jerry Blackwell; Alberto Moreno
Journal:  J Immunol       Date:  2016-08-29       Impact factor: 5.422

5.  Why functional pre-erythrocytic and bloodstage malaria vaccines fail: a meta-analysis of fully protective immunizations and novel immunological model.

Authors:  D Lys Guilbride; Pawel Gawlinski; Patrick D L Guilbride
Journal:  PLoS One       Date:  2010-05-19       Impact factor: 3.240

Review 6.  A retrospective evaluation of the role of T cells in the development of malaria vaccine.

Authors:  Moriya Tsuji
Journal:  Exp Parasitol       Date:  2009-11-26       Impact factor: 2.011

7.  Gamma delta T cells contribute to immunity against the liver stages of malaria in alpha beta T-cell-deficient mice.

Authors:  M Tsuji; P Mombaerts; L Lefrancois; R S Nussenzweig; F Zavala; S Tonegawa
Journal:  Proc Natl Acad Sci U S A       Date:  1994-01-04       Impact factor: 11.205

8.  Class II-restricted protective immunity induced by malaria sporozoites.

Authors:  Giane A Oliveira; Kota Arun Kumar; J Mauricio Calvo-Calle; Caroline Othoro; David Altszuler; Victor Nussenzweig; Elizabeth H Nardin
Journal:  Infect Immun       Date:  2007-12-26       Impact factor: 3.441

9.  Human T cell recognition of the blood stage antigen Plasmodium hypoxanthine guanine xanthine phosphoribosyl transferase (HGXPRT) in acute malaria.

Authors:  Tonia Woodberry; Alberto Pinzon-Charry; Kim A Piera; Yawalak Panpisutchai; Christian R Engwerda; Denise L Doolan; Ervi Salwati; Enny Kenangalem; Emiliana Tjitra; Ric N Price; Michael F Good; Nicholas M Anstey
Journal:  Malar J       Date:  2009-06-07       Impact factor: 2.979

Review 10.  Immunological mechanisms underlying protection mediated by RTS,S: a review of the available data.

Authors:  Vasee S Moorthy; W Ripley Ballou
Journal:  Malar J       Date:  2009-12-30       Impact factor: 2.979
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