| Literature DB >> 21461808 |
Isabelle Ourliac-Garnier1, Arturo Londoño-Vallejo.
Abstract
Length is a functional parameter of telomeres, the nucleoprotein structures that protect chromosome ends. The availability of highly specific, high-affinity probes for telomeric repeated sequences allowed the development of quantitative approaches aimed at measuring telomere length directly on chromosomes or in interphase nuclei. Here, we describe a general method for telomere quantitative FISH on metaphase chromosomes and discuss its most common applications in research.Mesh:
Year: 2011 PMID: 21461808 DOI: 10.1007/978-1-61779-092-8_3
Source DB: PubMed Journal: Methods Mol Biol ISSN: 1064-3745