Literature DB >> 21460803

Do cilia put brakes on the cell cycle?

Peter K Jackson.   

Abstract

Two papers in this issue show that dynein-binding proteins may regulate the G1-S transition through an effect on cilia. Nde1, a known partner of dynein light chain LC8, controls ciliary length in vitro and in zebrafish, and influences the G1-S progression. The phosphorylation of Tctex1, a dynein light chain, modulates cilia length and accelerates G1-S, thereby regulating proliferation-differentiation decisions in the developing mouse neocortex.
© 2011 Macmillan Publishers Limited. All rights reserved

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Year:  2011        PMID： 21460803     DOI： 10.1038/ncb0411-340

Source DB:  PubMed          Journal:  Nat Cell Biol        ISSN： 1465-7392            Impact factor:   28.824


  15 in total

1.  Primary cilia membrane assembly is initiated by Rab11 and transport protein particle II (TRAPPII) complex-dependent trafficking of Rabin8 to the centrosome.

Authors:  Christopher J Westlake; Lisa M Baye; Maxence V Nachury; Kevin J Wright; Karen E Ervin; Lilian Phu; Cecile Chalouni; John S Beck; Donald S Kirkpatrick; Diane C Slusarski; Val C Sheffield; Richard H Scheller; Peter K Jackson
Journal:  Proc Natl Acad Sci U S A       Date:  2011-01-27       Impact factor: 11.205

2.  A core complex of BBS proteins cooperates with the GTPase Rab8 to promote ciliary membrane biogenesis.

Authors:  Maxence V Nachury; Alexander V Loktev; Qihong Zhang; Christopher J Westlake; Johan Peränen; Andreas Merdes; Diane C Slusarski; Richard H Scheller; J Fernando Bazan; Val C Sheffield; Peter K Jackson
Journal:  Cell       Date:  2007-06-15       Impact factor: 41.582

Review 3.  Intraflagellar transport (IFT) role in ciliary assembly, resorption and signalling.

Authors:  Lotte B Pedersen; Joel L Rosenbaum
Journal:  Curr Top Dev Biol       Date:  2008       Impact factor: 4.897

Review 4.  The perennial organelle: assembly and disassembly of the primary cilium.

Authors:  E Scott Seeley; Maxence V Nachury
Journal:  J Cell Sci       Date:  2010-02-15       Impact factor: 5.285

5.  Centriole ciliation is related to quiescence and DNA synthesis in 3T3 cells.

Authors:  R W Tucker; A B Pardee; K Fujiwara
Journal:  Cell       Date:  1979-07       Impact factor: 41.582

6.  Mitotic spindle regulation by Nde1 controls cerebral cortical size.

Authors:  Yuanyi Feng; Christopher A Walsh
Journal:  Neuron       Date:  2004-10-14       Impact factor: 17.173

7.  HEF1-dependent Aurora A activation induces disassembly of the primary cilium.

Authors:  Elena N Pugacheva; Sandra A Jablonski; Tiffiney R Hartman; Elizabeth P Henske; Erica A Golemis
Journal:  Cell       Date:  2007-06-29       Impact factor: 41.582

8.  Nde1-mediated inhibition of ciliogenesis affects cell cycle re-entry.

Authors:  Sehyun Kim; Norann A Zaghloul; Ekaterina Bubenshchikova; Edwin C Oh; Susannah Rankin; Nicholas Katsanis; Tomoko Obara; Leonidas Tsiokas
Journal:  Nat Cell Biol       Date:  2011-03-13       Impact factor: 28.824

9.  A dynein light chain is essential for the retrograde particle movement of intraflagellar transport (IFT).

Authors:  G J Pazour; C G Wilkerson; G B Witman
Journal:  J Cell Biol       Date:  1998-05-18       Impact factor: 10.539

10.  Ciliary transition zone activation of phosphorylated Tctex-1 controls ciliary resorption, S-phase entry and fate of neural progenitors.

Authors:  Aiqun Li; Masaki Saito; Jen-Zen Chuang; Yun-Yu Tseng; Carlos Dedesma; Kazuhito Tomizawa; Taku Kaitsuka; Ching-Hwa Sung
Journal:  Nat Cell Biol       Date:  2011-03-13       Impact factor: 28.824
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  28 in total

Review 1.  Mechanism of ciliary disassembly.

Authors:  Yinwen Liang; Dan Meng; Bing Zhu; Junmin Pan
Journal:  Cell Mol Life Sci       Date:  2016-02-11       Impact factor: 9.261

Review 2.  New frontiers: discovering cilia-independent functions of cilia proteins.

Authors:  Anastassiia Vertii; Alison Bright; Benedicte Delaval; Heidi Hehnly; Stephen Doxsey
Journal:  EMBO Rep       Date:  2015-09-09       Impact factor: 8.807

3.  SIRT2 regulates ciliogenesis and contributes to abnormal centrosome amplification caused by loss of polycystin-1.

Authors:  Xia Zhou; Lucy X Fan; Keguo Li; Ramani Ramchandran; James P Calvet; Xiaogang Li
Journal:  Hum Mol Genet       Date:  2013-11-07       Impact factor: 6.150

4.  VDAC3 and Mps1 negatively regulate ciliogenesis.

Authors:  Shubhra Majumder; Harold A Fisk
Journal:  Cell Cycle       Date:  2013-02-06       Impact factor: 4.534

5.  Primary cilia control hedgehog signaling during muscle differentiation and are deregulated in rhabdomyosarcoma.

Authors:  Wenxiang Fu; Patrik Asp; Brian Canter; Brian David Dynlacht
Journal:  Proc Natl Acad Sci U S A       Date:  2014-06-09       Impact factor: 11.205

6.  Downregulation of PKD1 by shRNA results in defective osteogenic differentiation via cAMP/PKA pathway in human MG-63 cells.

Authors:  Ni Qiu; Honghao Zhou; Zhousheng Xiao
Journal:  J Cell Biochem       Date:  2012-03       Impact factor: 4.429

7.  Decreased FOXJ1 expression and its ciliogenesis programme in aggressive ependymoma and choroid plexus tumours.

Authors:  Malak S Abedalthagafi; Michael P Wu; Parker H Merrill; Ziming Du; Terri Woo; Shu-Hsien Sheu; Shelley Hurwitz; Keith L Ligon; Sandro Santagata
Journal:  J Pathol       Date:  2016-03       Impact factor: 7.996

8.  Primary cilia found on HeLa and other cancer cells.

Authors:  Tia J Kowal; Matthias M Falk
Journal:  Cell Biol Int       Date:  2015-08-06       Impact factor: 3.612

9.  Analysis from the perspective of cilia: the protective effect of PARP inhibitors on visual function during light-induced damage.

Authors:  Lin Che; Jing-Yao Song; Yan Lou; Guang-Yu Li
Journal:  Int Ophthalmol       Date:  2019-12-04       Impact factor: 2.031

Review 10.  The role of the cilium in normal and abnormal cell cycles: emphasis on renal cystic pathologies.

Authors:  Junmin Pan; Tamina Seeger-Nukpezah; Erica A Golemis
Journal:  Cell Mol Life Sci       Date:  2012-07-11       Impact factor: 9.261
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