Literature DB >> 21460493

Blood concentrations of chlorhexidine in hospitalized children undergoing daily chlorhexidine bathing.

Andrew Lee1, Robert Harlan, Autumn R Breaud, Kathleen Speck, Trish M Perl, William Clarke, Aaron M Milstone.   

Abstract

We collected serial blood samples from children in the intensive care unit who underwent daily bathing with 2% chlorhexidine gluconate (CHG)-impregnated cloths. Low concentrations of CHG were detected in a few blood samples, indicating absorption through intact skin. There was no suggestion that CHG accumulated in the blood with repeated exposures.

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Year:  2011        PMID： 21460493     DOI： 10.1086/659154

Source DB:  PubMed          Journal:  Infect Control Hosp Epidemiol        ISSN： 0899-823X            Impact factor:   3.254


  3 in total

1.  In vivo biocompatibility and in vitro efficacy of antimicrobial gendine-coated central catheters.

Authors:  Mohamed A Jamal; Ray Y Hachem; Joel Rosenblatt; Mark J McArthur; Edd Felix; Ying Jiang; Ramesh C Tailor; Issam Raad
Journal:  Antimicrob Agents Chemother       Date:  2015-06-29       Impact factor: 5.191

2.  Daily chlorhexidine bathing to reduce bacteraemia in critically ill children: a multicentre, cluster-randomised, crossover trial.

Authors:  Aaron M Milstone; Alexis Elward; Xiaoyan Song; Danielle M Zerr; Rachel Orscheln; Kathleen Speck; Daniel Obeng; Nicholas G Reich; Susan E Coffin; Trish M Perl
Journal:  Lancet       Date:  2013-01-28       Impact factor: 79.321

3.  Empirical power and sample size calculations for cluster-randomized and cluster-randomized crossover studies.

Authors:  Nicholas G Reich; Jessica A Myers; Daniel Obeng; Aaron M Milstone; Trish M Perl
Journal:  PLoS One       Date:  2012-04-27       Impact factor: 3.240
  3 in total

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