| Literature DB >> 21460022 |
Meghan Rioth1, Carole Anne Beauharnais, Francine Noel, Mine R Ikizler, Sapna Mehta, Yuwei Zhu, Carole A Long, Jean W Pape, Peter F Wright.
Abstract
Dengue is endemic to Haiti but not recognized as an important illness in the autochthonous population. To evaluate the prevalence of antibodies to dengue virus (DENV), serum samples from infants and young children 7-36 months of age (n = 166) were assayed by plaque reduction neutralization assays to each DENV serotype. Dengue virus serotype 1 had infected 40% of this study population, followed by serotype 2 (12%), serotype 3 (11%), and serotype 4 (2%). Fifty-three percent of infants and young children less than 12 months of age had already experienced DENV infection, and the seroprevalence of antibody to DENV increased to 65% by 36 months. Heterotypic antibody responses were an important component of the total dengue immunity profile.Entities:
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Year: 2011 PMID: 21460022 PMCID: PMC3062461 DOI: 10.4269/ajtmh.2011.10-0323
Source DB: PubMed Journal: Am J Trop Med Hyg ISSN: 0002-9637 Impact factor: 2.345