Literature DB >> 21458664

The evolving war on cancer.

Daniel A Haber1, Nathanael S Gray, Jose Baselga.   

Abstract

Building on years of basic scientific discovery, recent advances in the fields of cancer genetics and medicinal chemistry are now converging to revolutionize the treatment of cancer. Starting with serendipitous observations in rare subsets of cancer, a paradigm shift in clinical research is poised to ensure that new molecular insights are rapidly applied to shape emerging cancer therapies. Could this mark a turning point in the "War on Cancer"?
Copyright © 2011 Elsevier Inc. All rights reserved.

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Year:  2011        PMID： 21458664     DOI： 10.1016/j.cell.2011.03.026

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  89 in total

Review 1.  Clinical implementation of comprehensive strategies to characterize cancer genomes: opportunities and challenges.

Authors:  Laura E MacConaill; Paul Van Hummelen; Matthew Meyerson; William C Hahn
Journal:  Cancer Discov       Date:  2011-09       Impact factor: 39.397

2.  Translating cancer 'omics' to improved outcomes.

Authors:  Emily A Vucic; Kelsie L Thu; Keith Robison; Leszek A Rybaczyk; Raj Chari; Carlos E Alvarez; Wan L Lam
Journal:  Genome Res       Date:  2012-02       Impact factor: 9.043

3.  Basal but not luminal mammary epithelial cells require PI3K/mTOR signaling for Ras-driven overgrowth.

Authors:  Kristin A Plichta; Jessica L Mathers; Shelley A Gestl; Adam B Glick; Edward J Gunther
Journal:  Cancer Res       Date:  2012-09-24       Impact factor: 12.701

4.  Targeting PKCδ as a Therapeutic Strategy against Heterogeneous Mechanisms of EGFR Inhibitor Resistance in EGFR-Mutant Lung Cancer.

Authors:  Pei-Chih Lee; Yueh-Fu Fang; Hirohito Yamaguchi; Wei-Jan Wang; Tse-Ching Chen; Xuan Hong; Baozhen Ke; Weiya Xia; Yongkun Wei; Zhengyu Zha; Yan Wang; Han-Pin Kuo; Chih-Wei Wang; Chih-Yen Tu; Chia-Hung Chen; Wei-Chien Huang; Shu-Fen Chiang; Lei Nie; Junwei Hou; Chun-Te Chen; Longfei Huo; Wen-Hao Yang; Rong Deng; Katsuya Nakai; Yi-Hsin Hsu; Shih-Shin Chang; Tai-Jan Chiu; Jun Tang; Ran Zhang; Li Wang; Bingliang Fang; Ting Chen; Kwok-Kin Wong; Jennifer L Hsu; Mien-Chie Hung
Journal:  Cancer Cell       Date:  2018-12-10       Impact factor: 31.743

5.  An epigenetic mechanism of resistance to targeted therapy in T cell acute lymphoblastic leukemia.

Authors:  Birgit Knoechel; Justine E Roderick; Kaylyn E Williamson; Jiang Zhu; Jens G Lohr; Matthew J Cotton; Shawn M Gillespie; Daniel Fernandez; Manching Ku; Hongfang Wang; Federica Piccioni; Serena J Silver; Mohit Jain; Daniel Pearson; Michael J Kluk; Christopher J Ott; Leonard D Shultz; Michael A Brehm; Dale L Greiner; Alejandro Gutierrez; Kimberly Stegmaier; Andrew L Kung; David E Root; James E Bradner; Jon C Aster; Michelle A Kelliher; Bradley E Bernstein
Journal:  Nat Genet       Date:  2014-03-02       Impact factor: 38.330

6.  Loss of RBF1 changes glutamine catabolism.

Authors:  Brandon N Nicolay; Paulo A Gameiro; Katrin Tschöp; Michael Korenjak; Andreas M Heilmann; John M Asara; Gregory Stephanopoulos; Othon Iliopoulos; Nicholas J Dyson
Journal:  Genes Dev       Date:  2013-01-15       Impact factor: 11.361

7.  Stromal interactions as regulators of tumor growth and therapeutic response: A potential target for photodynamic therapy?

Authors:  Jonathan P Celli
Journal:  Isr J Chem       Date:  2012-07-24       Impact factor: 3.333

8.  Targeting 4-1BB costimulation to the tumor stroma with bispecific aptamer conjugates enhances the therapeutic index of tumor immunotherapy.

Authors:  Brett Schrand; Alexey Berezhnoy; Randall Brenneman; Anthony Williams; Agata Levay; Ling-Yuan Kong; Ganesh Rao; Shouhao Zhou; Amy B Heimberger; Eli Gilboa
Journal:  Cancer Immunol Res       Date:  2014-06-17       Impact factor: 11.151

Review 9.  Blood-based analyses of cancer: circulating tumor cells and circulating tumor DNA.

Authors:  Daniel A Haber; Victor E Velculescu
Journal:  Cancer Discov       Date:  2014-05-06       Impact factor: 39.397

Review 10.  Aging genomes: a necessary evil in the logic of life.

Authors:  Jan Vijg
Journal:  Bioessays       Date:  2014-01-25       Impact factor: 4.345
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