Jun-Beom Park1. 1. Department of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, Ann Arbor, MI, USA. jbassoonis@yahoo.co.kr
Abstract
OBJECTIVE: The objective of this study is to evaluate the use of tetracycline in a patient with peri-implantitis. BACKGROUND: Tetracycline is widely used in regeneration procedures owing to its positive effect with bone graft material, regeneration of extraction socket bone and its traditional antibacterial effect. However, there have been limited reports on bone graft procedures combined with tetracycline application in peri-implantitis. MATERIALS AND METHODS: The detoxification procedure was performed with chlorhexidine and tetracycline, and the defect area was grafted with a 4:1 volume ratio combination of deproteinised bovine bone mixed with tetracycline. RESULTS: Soft tissue healing was uneventful, and the treatment yielded improved clinical results with a reduced probing depth. CONCLUSIONS: Tetracycline was used in the treatment of peri-implantitis by burnishing the implant surface and applying tetracycline in conjunction with an osseous graft to the defect area. The treatment of peri-implantitis with tetracycline seemed to show improved clinical results up to the follow-up period.
OBJECTIVE: The objective of this study is to evaluate the use of tetracycline in a patient with peri-implantitis. BACKGROUND:Tetracycline is widely used in regeneration procedures owing to its positive effect with bone graft material, regeneration of extraction socket bone and its traditional antibacterial effect. However, there have been limited reports on bone graft procedures combined with tetracycline application in peri-implantitis. MATERIALS AND METHODS: The detoxification procedure was performed with chlorhexidine and tetracycline, and the defect area was grafted with a 4:1 volume ratio combination of deproteinised bovine bone mixed with tetracycline. RESULTS: Soft tissue healing was uneventful, and the treatment yielded improved clinical results with a reduced probing depth. CONCLUSIONS:Tetracycline was used in the treatment of peri-implantitis by burnishing the implant surface and applying tetracycline in conjunction with an osseous graft to the defect area. The treatment of peri-implantitis with tetracycline seemed to show improved clinical results up to the follow-up period.