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Literature DB >> 214571

Detergent-inhibited, heat-labile nucleoside triphosphatase in cores of avian myeloblastosis virus.

Abstract

Endogenous DNA synthesis was studied in isolated core particles of avian myeloblastosis virus. It was found that cores contained an enzymatic activity which rapidly converted the added nucleoside triphosphates to diphosphates (but not further) at 0 degrees C, thus inhibiting DNA synthesis. This triphosphatase probably originates from the viral membranes. In the cores the enzyme is completely inactivated by low concentrations (0.02%) of Nonident P-40. Also, the enzyme is very thermolabile and denatures rapidly at 38 degrees C.

Entities: Chemical Species

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Year: 1978 PMID： 214571 PMCID： PMC354291

Source DB: PubMed Journal: J Virol ISSN： 0022-538X Impact factor: 5.103

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References

19 in total

7. In vitro transcription of DNA from the 70S RNA of Rous sarcoma virus: identification and characterization of various size classes of DNA transcripts.

Authors: M S Collett; A J Faras
Journal: J Virol Date: 1975-11 Impact factor: 5.103

8. Surface-active agents for isolation of the core component of avian myeloblastosis virus.

Authors: K Stromberg
Journal: J Virol Date: 1972-04 Impact factor: 5.103

9. Mechanistic independence of avian myeloblastosis virus DNA polymerase and ribonuclease H.

Authors: L C Brewer; R D Wells
Journal: J Virol Date: 1974-12 Impact factor: 5.103

10. Structural studies of avian myeloblastosis virus: comparison of polypeptides in virion and core component by dodecyl sulfate-polyacrylamide gel electrophoresis.

Authors: K Stromberg; N E Hurley; N L Davis; R R Rueckert; E Fleissner
Journal: J Virol Date: 1974-02 Impact factor: 5.103

Detergent-inhibited, heat-labile nucleoside triphosphatase in cores of avian myeloblastosis virus.

Review 1. AVIAN VIRUS GROWTHS AND THEIR ETIOLOGIC AGENTS.

2. In vitro synthesis of full-length DNA transcripts of Rous sarcoma virus RNA by viral DNA polymerase.

Review 3. RNA-directed DNA synthesis and RNA tumor viruses.

4. Synthesis and characterization of the duplex block polymer d(C15A15)-d(T15G15).

5. High molecular weight RNAs from Rous sarcoma virus and Moloney murine leukemia virus contain two subunits.

6. Transcription of 70S RNA by DNA polymerases from mammalian RNA viruses.

7. In vitro transcription of DNA from the 70S RNA of Rous sarcoma virus: identification and characterization of various size classes of DNA transcripts.

8. Surface-active agents for isolation of the core component of avian myeloblastosis virus.

9. Mechanistic independence of avian myeloblastosis virus DNA polymerase and ribonuclease H.

10. Structural studies of avian myeloblastosis virus: comparison of polypeptides in virion and core component by dodecyl sulfate-polyacrylamide gel electrophoresis.