Copper-catalyzed cascade synthesis of benzimidazoquinazoline derivatives under mild condition.

A convenient and efficient copper-catalyzed cascade method has been developed for the synthesis of benzimidazoquinazoline derivatives via reactions of readily available substituted 2-(2-halophenyl)benzoimidazoles with amidines or guanidine under mild conditions (even at room temperature). © The Royal Society of Chemistry 2011