Literature DB >> 21455474

Kingella kingae spondylodiscitis in young children: toward a new approach for bacteriological investigations? A preliminary report.

Dimitri Ceroni, Abdessalam Cherkaoui, André Kaelin, Jacques Schrenzel.   

Abstract

As the result of improved bacteriological techniques, Kingella kingae is a slow-growing Gram-negative coccobacillus that is emerging as an important cause of spondylodiscitis in children younger than 3 years of age. The high pharyngeal carrier rates of this slow-growing Gram-negative coccobacillus combined with the low incidence of identified K. kingae infections is possibly explained by a low virulence of this bacterium. The use of specific real-time polymerase chain reaction (PCR) on blood samples and throat swabs opens new prospects in the bacteriological investigations of young children suspected to have spondylodiscitis, an approach that could prevent, in the future, unnecessary invasive interventions.

Entities:  

Keywords:  Children; Kingella kingae; Osteoarticular infection; Spondylodiscitis; qPCR

Year:  2010        PMID: 21455474      PMCID: PMC2839857          DOI: 10.1007/s11832-009-0233-2

Source DB:  PubMed          Journal:  J Child Orthop        ISSN: 1863-2521            Impact factor:   1.548


  24 in total

1.  Discitis and vertebral osteomyelitis in children: an 18-year review.

Authors:  M Fernandez; C L Carrol; C J Baker
Journal:  Pediatrics       Date:  2000-06       Impact factor: 7.124

2.  Osteoarticular infections caused by Kingella kingae in children: contribution of polymerase chain reaction to the microbiologic diagnosis.

Authors:  Kaoutar Moumile; Jacques Merckx; Christophe Glorion; Patrick Berche; Agnes Ferroni
Journal:  Pediatr Infect Dis J       Date:  2003-09       Impact factor: 2.129

3.  Kingella kingae osteoarthritis and osteomyelitis in children.

Authors:  J L Clément; J Berard; J P Cahuzac; J Gaubert
Journal:  J Pediatr Orthop       Date:  1988 Jan-Feb       Impact factor: 2.324

4.  Observations on the venous drainage of the human vertebral body.

Authors:  H V Crock; H Yoshizawa; S K Kame
Journal:  J Bone Joint Surg Br       Date:  1973-08

5.  Intervertebral discitis in children: a review of 12 cases.

Authors:  N Ventura; E Gonzalez; L Terricabras; A Salvador; M Cabrera
Journal:  Int Orthop       Date:  1996       Impact factor: 3.075

6.  Nontuberculous spondylodiscitis in children.

Authors:  Emmanuel Garron; Elke Viehweger; Frank Launay; Jean Marc Guillaume; Jean Luc Jouve; Gérard Bollini
Journal:  J Pediatr Orthop       Date:  2002 May-Jun       Impact factor: 2.324

7.  Identification and characterization of an RTX toxin in the emerging pathogen Kingella kingae.

Authors:  Thomas E Kehl-Fie; Joseph W St Geme
Journal:  J Bacteriol       Date:  2006-11-10       Impact factor: 3.490

8.  Molecular diagnosis of Kingella kingae osteoarticular infections by specific real-time PCR assay.

Authors:  Abdessalam Cherkaoui; Dimitri Ceroni; Stéphane Emonet; Yan Lefevre; Jacques Schrenzel
Journal:  J Med Microbiol       Date:  2009-01       Impact factor: 2.472

9.  New real-time PCR-based method for Kingella kingae DNA detection: application to samples collected from 89 children with acute arthritis.

Authors:  Brice Ilharreborde; Philippe Bidet; Mathie Lorrot; Julien Even; Patricia Mariani-Kurkdjian; Sandrine Liguori; Christine Vitoux; Yann Lefevre; Catherine Doit; Franck Fitoussi; Georges Penneçot; Edouard Bingen; Keyvan Mazda; Stéphane Bonacorsi
Journal:  J Clin Microbiol       Date:  2009-04-15       Impact factor: 5.948

10.  Nonspecific diskitis in children. A nonmicrobial disease?

Authors:  S Ryöppy; J Jääskeläinen; J Rapola; A Alberty
Journal:  Clin Orthop Relat Res       Date:  1993-12       Impact factor: 4.176

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  7 in total

Review 1.  Kingella kingae: carriage, transmission, and disease.

Authors:  Pablo Yagupsky
Journal:  Clin Microbiol Rev       Date:  2015-01       Impact factor: 26.132

2.  Characterization of TEM-1 β-Lactamase-Producing Kingella kingae Clinical Isolates.

Authors:  Anushree Banerjee; Jeffrey B Kaplan; Amenah Soherwardy; Yoav Nudell; Grace A Mackenzie; Shannon Johnson; Nataliya V Balashova
Journal:  Antimicrob Agents Chemother       Date:  2013-06-24       Impact factor: 5.191

3.  Molecular Tests That Target the RTX Locus Do Not Distinguish between Kingella kingae and the Recently Described Kingella negevensis Species.

Authors:  Nawal El Houmami; Janek Bzdrenga; Guillaume André Durand; Philippe Minodier; Hervé Seligmann; Elsa Prudent; Sofiane Bakour; Stéphane Bonacorsi; Didier Raoult; Pablo Yagupsky; Pierre-Edouard Fournier
Journal:  J Clin Microbiol       Date:  2017-08-09       Impact factor: 5.948

4.  RTX toxin plays a key role in Kingella kingae virulence in an infant rat model.

Authors:  Dennis W Chang; Yoav A Nudell; Jenny Lau; Eleonora Zakharian; Nataliya V Balashova
Journal:  Infect Immun       Date:  2014-03-24       Impact factor: 3.441

5.  Kingella kingae septic arthritis in children: recognising an elusive pathogen.

Authors:  Nicole Williams; Celia Cooper; Peter Cundy
Journal:  J Child Orthop       Date:  2014-01-23       Impact factor: 1.548

6.  Progression of Infection after Surgical CT Navigation-Assisted Aspiration Biopsy of a Vertebral Abscess.

Authors:  Vasiliki Spyropoulou; Raimunda Valaikaite; Amira Dhouib; Romain Dayer; Dimitri Ceroni
Journal:  Case Rep Orthop       Date:  2016-02-01

Review 7.  Pharyngeal Colonization by Kingella kingae, Transmission, and Pathogenesis of Invasive Infections: A Narrative Review.

Authors:  Pablo Yagupsky
Journal:  Microorganisms       Date:  2022-03-17
  7 in total

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