Literature DB >> 21455211

Nondividing cells: a safer bet for integrating vectors?

Troy Brady1, Frederic D Bushman.   

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Year:  2011        PMID： 21455211      PMCID： PMC3070107          DOI： 10.1038/mt.2011.40

Source DB:  PubMed          Journal:  Mol Ther        ISSN： 1525-0016            Impact factor:   11.454


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  16 in total

1.  Rational design of small-molecule inhibitors of the LEDGF/p75-integrase interaction and HIV replication.

Authors:  Frauke Christ; Arnout Voet; Arnaud Marchand; Stefan Nicolet; Belete A Desimmie; Damien Marchand; Dorothée Bardiot; Nam Joo Van der Veken; Barbara Van Remoortel; Sergei V Strelkov; Marc De Maeyer; Patrick Chaltin; Zeger Debyser
Journal:  Nat Chem Biol       Date:  2010-05-16       Impact factor: 15.040

2.  Integration site selection by HIV-based vectors in dividing and growth-arrested IMR-90 lung fibroblasts.

Authors:  Angela Ciuffi; Richard S Mitchell; Christian Hoffmann; Jeremy Leipzig; Paul Shinn; Joseph R Ecker; Frederic D Bushman
Journal:  Mol Ther       Date:  2005-12-01       Impact factor: 11.454

3.  Modification of integration site preferences of an HIV-1-based vector by expression of a novel synthetic protein.

Authors:  Robert M Silvers; Johanna A Smith; Michael Schowalter; Samuel Litwin; Zhihui Liang; Kyla Geary; René Daniel
Journal:  Hum Gene Ther       Date:  2010-03       Impact factor: 5.695

4.  Lens epithelium-derived growth factor fusion proteins redirect HIV-1 DNA integration.

Authors:  Andrea L Ferris; Xiaolin Wu; Christina M Hughes; Claudia Stewart; Steven J Smith; Thomas A Milne; Gang G Wang; Ming-Chieh Shun; C David Allis; Alan Engelman; Stephen H Hughes
Journal:  Proc Natl Acad Sci U S A       Date:  2010-02-01       Impact factor: 11.205

5.  Transfusion independence and HMGA2 activation after gene therapy of human β-thalassaemia.

Authors:  Marina Cavazzana-Calvo; Emmanuel Payen; Olivier Negre; Gary Wang; Kathleen Hehir; Floriane Fusil; Julian Down; Maria Denaro; Troy Brady; Karen Westerman; Resy Cavallesco; Beatrix Gillet-Legrand; Laure Caccavelli; Riccardo Sgarra; Leila Maouche-Chrétien; Françoise Bernaudin; Robert Girot; Ronald Dorazio; Geert-Jan Mulder; Axel Polack; Arthur Bank; Jean Soulier; Jérôme Larghero; Nabil Kabbara; Bruno Dalle; Bernard Gourmel; Gérard Socie; Stany Chrétien; Nathalie Cartier; Patrick Aubourg; Alain Fischer; Kenneth Cornetta; Frédéric Galacteros; Yves Beuzard; Eliane Gluckman; Frederick Bushman; Salima Hacein-Bey-Abina; Philippe Leboulch
Journal:  Nature       Date:  2010-09-16       Impact factor: 49.962

6.  LEDGF hybrids efficiently retarget lentiviral integration into heterochromatin.

Authors:  Rik Gijsbers; Keshet Ronen; Sofie Vets; Nirav Malani; Jan De Rijck; Melissa McNeely; Frederic D Bushman; Zeger Debyser
Journal:  Mol Ther       Date:  2010-01-05       Impact factor: 11.454

7.  A role for LEDGF/p75 in targeting HIV DNA integration.

Authors:  Angela Ciuffi; Manuel Llano; Eric Poeschla; Christian Hoffmann; Jeremy Leipzig; Paul Shinn; Joseph R Ecker; Frederic Bushman
Journal:  Nat Med       Date:  2005-11-27       Impact factor: 53.440

8.  Lentiviral vector integration profiles differ in rodent postmitotic tissues.

Authors:  Cynthia C Bartholomae; Anne Arens; Kamaljit S Balaggan; Rafael J Yáñez-Muñoz; Eugenio Montini; Steven J Howe; Anna Paruzynski; Bernhard Korn; Jens Uwe Appelt; Angus Macneil; Daniela Cesana; Ulrich Abel; Hanno Glimm; Luigi Naldini; Robin R Ali; Adrian J Thrasher; Christof von Kalle; Manfred Schmidt
Journal:  Mol Ther       Date:  2011-03-01       Impact factor: 11.454

9.  Large-scale analysis of adeno-associated virus vector integration sites in normal human cells.

Authors:  Daniel G Miller; Grant D Trobridge; Lisa M Petek; Michael A Jacobs; Rajinder Kaul; David W Russell
Journal:  J Virol       Date:  2005-09       Impact factor: 5.103

10.  Identification of an evolutionarily conserved domain in human lens epithelium-derived growth factor/transcriptional co-activator p75 (LEDGF/p75) that binds HIV-1 integrase.

Authors:  Peter Cherepanov; Eric Devroe; Pamela A Silver; Alan Engelman
Journal:  J Biol Chem       Date:  2004-09-14       Impact factor: 5.157
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  1 in total

Review 1.  Evaluating risks of insertional mutagenesis by DNA transposons in gene therapy.

Authors:  Perry B Hackett; David A Largaespada; Kirsten C Switzer; Laurence J N Cooper
Journal:  Transl Res       Date:  2013-01-10       Impact factor: 7.012
  1 in total

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