Peggy S Odegard1, Mary M Janci2, Melanie P Foeppel3, Jennifer R Beach2, Dace L Trence2. 1. The Department of Medicine, University of Washington, Seattle, Washington (Dr Odegard, Dr Trence) 2. The Diabetes Care Center, University of Washington Medical Center, Seattle, Washington (Ms Janci, Dr Beach, Dr Trence) 3. The School of Pharmacy, Pacific University, Forest Grove, Oregon (Dr Foeppel)
Abstract
OBJECTIVES: This study sought to describe the prevalence of supplement use by those with diabetes mellitus receiving care at an academic outpatient diabetes care center and to identify any association of supplement use with glycemic control. METHODS: This study is based on a retrospective audit of provider-verified and patient-self-reported medication and supplement use by adults with diabetes at the University of Washington Diabetes Care Center during four 2-week periods from fall 2006 through summer 2007 (1 period per season). RESULTS: Verified medication and supplement histories for 459 adults demonstrated a per-person average use of 7 ± 4.1 prescription medicines and 0.4 ± 0.9 over-the-counter medicines daily, with 55% using some form of vitamin, mineral, or nonvitamin-nonmineral supplement on a daily basis. The rate of nonvitamin-nonmineral use was nearly twice that for type 2 diabetes mellitus as for type 1 diabetes mellitus (39.3% vs 20.3%), and A1c was lower in those using any supplement compared to those not using supplements. Vitamin use was associated with reduced A1c; however, this relationship did not hold at A1c < 7.0%. CONCLUSIONS: The findings highlight the prevalence of supplement use in diabetes mellitus and association of supplement use with improved glycemic control. Findings are limited by the retrospective design.
OBJECTIVES: This study sought to describe the prevalence of supplement use by those with diabetes mellitus receiving care at an academic outpatientdiabetes care center and to identify any association of supplement use with glycemic control. METHODS: This study is based on a retrospective audit of provider-verified and patient-self-reported medication and supplement use by adults with diabetes at the University of Washington Diabetes Care Center during four 2-week periods from fall 2006 through summer 2007 (1 period per season). RESULTS: Verified medication and supplement histories for 459 adults demonstrated a per-person average use of 7 ± 4.1 prescription medicines and 0.4 ± 0.9 over-the-counter medicines daily, with 55% using some form of vitamin, mineral, or nonvitamin-nonmineral supplement on a daily basis. The rate of nonvitamin-nonmineral use was nearly twice that for type 2 diabetes mellitus as for type 1 diabetes mellitus (39.3% vs 20.3%), and A1c was lower in those using any supplement compared to those not using supplements. Vitamin use was associated with reduced A1c; however, this relationship did not hold at A1c < 7.0%. CONCLUSIONS: The findings highlight the prevalence of supplement use in diabetes mellitus and association of supplement use with improved glycemic control. Findings are limited by the retrospective design.
Authors: Laura C Ortinau; R Taylor Pickering; Karen J Nickelson; Kelly L Stromsdorfer; Chaitasi Y Naik; Rebecca A Haynes; Dale E Bauman; R Scott Rector; Kevin L Fritsche; James W Perfield Journal: ISRN Endocrinol Date: 2012-11-14