Literature DB >> 21454599

Mitogen-activated protein kinase kinase 4 deficiency in cardiomyocytes causes connexin 43 reduction and couples hypertrophic signals to ventricular arrhythmogenesis.

Min Zi1, Tomomi E Kimura, Wei Liu, Jiawei Jin, Jonathan Higham, Sanjay Kharche, Guoliang Hao, Ying Shi, Weijian Shen, Sukhpal Prehar, Aleksandr Mironov, Ludwig Neyses, Marti F A Bierhuizen, Mark R Boyett, Henggui Zhang, Ming Lei, Elizabeth J Cartwright, Xin Wang.   

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Year:  2011        PMID： 21454599      PMCID： PMC3093857          DOI： 10.1074/jbc.M111.228791

Source DB:  PubMed          Journal:  J Biol Chem        ISSN： 0021-9258            Impact factor:   5.157


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  37 in total

Review 1.  Connexin phosphorylation as a regulatory event linked to gap junction internalization and degradation.

Authors:  Dale W Laird
Journal:  Biochim Biophys Acta       Date:  2005-06-10

2.  Cardiac-specific loss of N-cadherin leads to alteration in connexins with conduction slowing and arrhythmogenesis.

Authors:  Jifen Li; Vickas V Patel; Igor Kostetskii; Yanming Xiong; Antony F Chu; Jason T Jacobson; Cindy Yu; Gregory E Morley; Jeffery D Molkentin; Glenn L Radice
Journal:  Circ Res       Date:  2005-08-11       Impact factor: 17.367

Review 3.  Dependence of electrical coupling on mechanical coupling in cardiac myocytes: insights gained from cardiomyopathies caused by defects in cell-cell connections.

Authors:  Jeffrey E Saffitz
Journal:  Ann N Y Acad Sci       Date:  2005-06       Impact factor: 5.691

4.  Analysis of Connexin43 phosphorylated at S325, S328 and S330 in normoxic and ischemic heart.

Authors:  Paul D Lampe; Cynthia D Cooper; Timothy J King; Janis M Burt
Journal:  J Cell Sci       Date:  2006-08-01       Impact factor: 5.285

5.  Induced deletion of the N-cadherin gene in the heart leads to dissolution of the intercalated disc structure.

Authors:  Igor Kostetskii; Jifen Li; Yanming Xiong; Rong Zhou; Victor A Ferrari; Vickas V Patel; Jeffery D Molkentin; Glenn L Radice
Journal:  Circ Res       Date:  2005-01-20       Impact factor: 17.367

6.  Reduced content of connexin43 gap junctions in ventricular myocardium from hypertrophied and ischemic human hearts.

Authors:  N S Peters; C R Green; P A Poole-Wilson; N J Severs
Journal:  Circulation       Date:  1993-09       Impact factor: 29.690

7.  Larger cell size in rabbits with heart failure increases myocardial conduction velocity and QRS duration.

Authors:  Rob F Wiegerinck; Arie O Verkerk; Charly N Belterman; Toon A B van Veen; Antonius Baartscheer; Tobias Opthof; Ronald Wilders; Jacques M T de Bakker; Ruben Coronel
Journal:  Circulation       Date:  2006-02-06       Impact factor: 29.690

8.  C-terminal truncation of connexin43 changes number, size, and localization of cardiac gap junction plaques.

Authors:  Karen Maass; Junko Shibayama; Sharon E Chase; Klaus Willecke; Mario Delmar
Journal:  Circ Res       Date:  2007-10-11       Impact factor: 17.367

Review 9.  Physiological roles of MKK4 and MKK7: insights from animal models.

Authors:  Xin Wang; Auriane Destrument; Cathy Tournier
Journal:  Biochim Biophys Acta       Date:  2006-11-10

10.  Targeted deletion of the mitogen-activated protein kinase kinase 4 gene in the nervous system causes severe brain developmental defects and premature death.

Authors:  Xin Wang; Bagirathy Nadarajah; Andrew C Robinson; Barry W McColl; Jia-Wei Jin; Federico Dajas-Bailador; Raymond P Boot-Handford; Cathy Tournier
Journal:  Mol Cell Biol       Date:  2007-09-17       Impact factor: 4.272
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  7 in total

Review 1.  Connexins in the Heart: Regulation, Function and Involvement in Cardiac Disease.

Authors:  Antonio Rodríguez-Sinovas; Jose Antonio Sánchez; Laura Valls-Lacalle; Marta Consegal; Ignacio Ferreira-González
Journal:  Int J Mol Sci       Date:  2021-04-23       Impact factor: 5.923

Review 2.  Animal Models to Study Cardiac Arrhythmias.

Authors:  Daniel J Blackwell; Jeffrey Schmeckpeper; Bjorn C Knollmann
Journal:  Circ Res       Date:  2022-06-09       Impact factor: 23.213

Review 3.  Murine Electrophysiological Models of Cardiac Arrhythmogenesis.

Authors:  Christopher L-H Huang
Journal:  Physiol Rev       Date:  2017-01       Impact factor: 37.312

4.  Hyperthermia differently affects connexin43 expression and gap junction permeability in skeletal myoblasts and HeLa cells.

Authors:  Ieva Antanavičiūtė; Vida Mildažienė; Edgaras Stankevičius; Thomas Herdegen; Vytenis Arvydas Skeberdis
Journal:  Mediators Inflamm       Date:  2014-07-20       Impact factor: 4.711

5.  Antiarrhythmic effect of sevoflurane as an additive to HTK solution on reperfusion arrhythmias induced by hypothermia and ischaemia is associated with the phosphorylation of connexin 43 at serine 368.

Authors:  Wei Chao Li; Hong Gao; Ju Gao; Zi Jun Wang
Journal:  BMC Anesthesiol       Date:  2019-01-08       Impact factor: 2.217

Review 6.  JNK and cardiometabolic dysfunction.

Authors:  Siobhan M Craige; Kai Chen; Robert M Blanton; John F Keaney; Shashi Kant
Journal:  Biosci Rep       Date:  2019-07-18       Impact factor: 3.840

7.  Mkk4 is a negative regulator of the transforming growth factor beta 1 signaling associated with atrial remodeling and arrhythmogenesis with age.

Authors:  Laura Davies; Jiawei Jin; Weijin Shen; Hoyee Tsui; Ying Shi; Yanwen Wang; Yanmin Zhang; Guoliang Hao; Jingjing Wu; Si Chen; James A Fraser; Nianguo Dong; Vincent Christoffels; Ursula Ravens; Christopher L-H Huang; Henggui Zhang; Elizabeth J Cartwright; Xin Wang; Ming Lei
Journal:  J Am Heart Assoc       Date:  2014-04-10       Impact factor: 5.501
  7 in total

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