Literature DB >> 21454469

Dysregulation of the HIF pathway due to VHL mutation causing severe erythrocytosis and pulmonary arterial hypertension.

Jonathan Bond, Daniel P Gale, Thomas Connor, Stuart Adams, Jasper de Boer, Duncan M Gascoyne, Owen Williams, Patrick H Maxwell, Philip J Ancliff.   

Abstract

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Year:  2011        PMID： 21454469     DOI： 10.1182/blood-2010-12-327569

Source DB:  PubMed          Journal:  Blood        ISSN： 0006-4971            Impact factor:   22.113


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  19 in total

Review 1.  Hypoxia-inducible factor signaling in pulmonary hypertension.

Authors:  Soni Savai Pullamsetti; Argen Mamazhakypov; Norbert Weissmann; Werner Seeger; Rajkumar Savai
Journal:  J Clin Invest       Date:  2020-11-02       Impact factor: 14.808

2.  HIF-1 directly induces TET3 expression to enhance 5-hmC density and induce erythroid gene expression in hypoxia.

Authors:  John Z Cao; Hui Liu; Amittha Wickrema; Lucy A Godley
Journal:  Blood Adv       Date:  2020-07-14

3.  Protein tyrosine phosphatase ζ enhances proliferation by increasing β-catenin nuclear expression in VHL-inactive human renal cell carcinoma cells.

Authors:  Donghao Shang; Xiuhong Xu; Daye Wang; Yong Li; Yuting Liu
Journal:  World J Urol       Date:  2013-04-16       Impact factor: 4.226

4.  Novel homozygous VHL mutation in exon 2 is associated with congenital polycythemia but not with cancer.

Authors:  Lucie Lanikova; Felipe Lorenzo; Chunzhang Yang; Hari Vankayalapati; Richard Drachtman; Vladimir Divoky; Josef T Prchal
Journal:  Blood       Date:  2013-03-28       Impact factor: 22.113

Review 5.  HIF prolyl hydroxylase inhibitors for the treatment of renal anaemia and beyond.

Authors:  Patrick H Maxwell; Kai-Uwe Eckardt
Journal:  Nat Rev Nephrol       Date:  2015-12-14       Impact factor: 28.314

6.  Bone marrow findings of the newly described TEMPI syndrome: when erythrocytosis and plasma cell dyscrasia coexist.

Authors:  Flavia G Rosado; Jennifer L Oliveira; Aliya R Sohani; Wilfried Schroyens; David B Sykes; Saad S Kenderian; Martha Q Lacy; Robert A Kyle; James D Hoyer
Journal:  Mod Pathol       Date:  2014-09-12       Impact factor: 7.842

7.  Deletion of iron regulatory protein 1 causes polycythemia and pulmonary hypertension in mice through translational derepression of HIF2α.

Authors:  Manik C Ghosh; De-Liang Zhang; Suh Young Jeong; Gennadiy Kovtunovych; Hayden Ollivierre-Wilson; Audrey Noguchi; Tiffany Tu; Thomas Senecal; Gabrielle Robinson; Daniel R Crooks; Wing-Hang Tong; Kavitha Ramaswamy; Anamika Singh; Brian B Graham; Rubin M Tuder; Zu-Xi Yu; Michael Eckhaus; Jaekwon Lee; Danielle A Springer; Tracey A Rouault
Journal:  Cell Metab       Date:  2013-02-05       Impact factor: 27.287

8.  Genetic evidence of a precisely tuned dysregulation in the hypoxia signaling pathway during oncogenesis.

Authors:  Sophie Couvé; Charline Ladroue; Elodie Laine; Karène Mahtouk; Justine Guégan; Sophie Gad; Hélène Le Jeune; Marion Le Gentil; Gregory Nuel; William Y Kim; Bernard Lecomte; Jean-Christophe Pagès; Christine Collin; Françoise Lasne; Patrick R Benusiglio; Brigitte Bressac-de Paillerets; Jean Feunteun; Vladimir Lazar; Anne-Paule Gimenez-Roqueplo; Nathalie M Mazure; Philippe Dessen; Luba Tchertanov; David R Mole; William Kaelin; Peter Ratcliffe; Stéphane Richard; Betty Gardie
Journal:  Cancer Res       Date:  2014-11-04       Impact factor: 12.701

Review 9.  The endothelial ADMA/NO pathway in hypoxia-related chronic respiratory diseases.

Authors:  Nicole Lüneburg; Lars Harbaum; Jan K Hennigs
Journal:  Biomed Res Int       Date:  2014-02-25       Impact factor: 3.411

10.  Contrasting effects of ascorbate and iron on the pulmonary vascular response to hypoxia in humans.

Authors:  Nick P Talbot; Quentin P Croft; M Kate Curtis; Brandon E Turner; Keith L Dorrington; Peter A Robbins; Thomas G Smith
Journal:  Physiol Rep       Date:  2014-12-11
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