| Literature DB >> 21454394 |
Benjamin Wright1, Angela Summers, John Fenner, Richard Gillott, Charles E Hutchinson, Paul A Spencer, Martin Wilkie, Helen Hurst, Sarah Herrick, Paul Brenchley, Titus Augustine, Karna D Bardhan.
Abstract
Encapsulating peritoneal sclerosis (EPS) is an uncommon complication of peritoneal dialysis (PD), with high mortality and morbidity. The peritoneum thickens, dysfunctions, and forms a cocoon that progressively "strangulates" the small intestine, causing malnutrition, ischemia, and infarction. There is as yet no reliable noninvasive means of diagnosis, but recent developments in image analysis of cine magnetic resonance imaging for the recognition of adhesions offers a way forward. We used this protocol before surgery in 3 patients with suspected EPS. Image analysis revealed patterns of abdominal movement that were markedly different from the patterns in healthy volunteers. The volunteers showed marked movement throughout the abdomen; in contrast, movement in EPS patients was restricted to just below the diaphragm. This clear difference provides early "proof of principle" of the approach that we have developed.Entities:
Mesh:
Year: 2011 PMID: 21454394 DOI: 10.3747/pdi.2010.00078
Source DB: PubMed Journal: Perit Dial Int ISSN: 0896-8608 Impact factor: 1.756