BACKGROUND: Renal cell carcinoma (RCC) during pregnancy is rare. Volume doubling time for RCC is estimated to be 72 weeks. CASE: A 28-year-old woman was assessed for macroscopic hematuria at 21 weeks' gestation. A renal ultrasound revealed a 3.4 cm right renal mass. After MRI, the most likely diagnosis seemed to be angiomyolipoma. The patient opted for conservative management, and the pregnancy continued to almost 36 weeks, at which time the mass had tripled in size. Laparoscopic nephrectomy was performed four days after delivery, and pathological examination revealed a 9.3 cm renal cell carcinoma. Three months later, multiple metastases were identified, which were resistant to targeted therapies. The patient died 12 months postpartum. CONCLUSION: Although renal tumours during pregnancy have been reported, this is the first report of a fatal fast-growing renal tumour.
BACKGROUND:Renal cell carcinoma (RCC) during pregnancy is rare. Volume doubling time for RCC is estimated to be 72 weeks. CASE: A 28-year-old woman was assessed for macroscopic hematuria at 21 weeks' gestation. A renal ultrasound revealed a 3.4 cm right renal mass. After MRI, the most likely diagnosis seemed to be angiomyolipoma. The patient opted for conservative management, and the pregnancy continued to almost 36 weeks, at which time the mass had tripled in size. Laparoscopic nephrectomy was performed four days after delivery, and pathological examination revealed a 9.3 cm renal cell carcinoma. Three months later, multiple metastases were identified, which were resistant to targeted therapies. The patient died 12 months postpartum. CONCLUSION: Although renal tumours during pregnancy have been reported, this is the first report of a fatal fast-growing renal tumour.
Authors: Zsolt Domján; Endre Holman; Noémi Bordás; Alexander Stephan Dákay; Kiarash Bahrehmand; István Buzogány Journal: Int Urol Nephrol Date: 2014-05-07 Impact factor: 2.370
Authors: Anna Scavuzzo; Zael Santana Rios; Cristobal Diaz-Gomez; Beatriz Varguez Gonzalez; Victor Osornio-Sanchez; Edgar Bravo-Castro; Edgar Linden-Castro; Pedro Martinez-Cervera; Miguel Angel Jimenez-Rios Journal: Urol Case Rep Date: 2017-05-11
Authors: Ercan Yilmaz; Fatih Oguz; Gorkem Tuncay; Rauf Melekoglu; Ali Beytur; Ebru Inci Coskun; Ali Gunes Journal: J Int Med Res Date: 2018-06-08 Impact factor: 1.671
Authors: László Mangel; Krisztina Bíró; István Battyáni; Péter Göcze; Tamás Tornóczky; Endre Kálmán Journal: BMC Cancer Date: 2015-12-24 Impact factor: 4.430