Literature DB >> 21453229

The use of an implantable Doppler flow probe in kidney transplantation: first report in the literature.

Jeremy Crane1, Nadey Hakim.   

Abstract

OBJECTIVES: After a kidney transplant, surveillance of the graft blood supply is crucial. Any delay in detecting compromised graft perfusion affects organ survival. Current practice uses Doppler ultrasound to monitor vessel patency and graft perfusion and is performed repeatedly after kidney and pancreas transplant. We have used an implantable probe that allows for easy vessel attachment and safe, continuous, audible monitoring of vascular anastomoses. It has been used to observe microvascular tissue transplants, free flaps, and pediatric liver transplants, but as yet, it has not been used to monitor kidney allografts. We feel a transplanted kidney could benefit greatly from continuous blood flow monitoring.
MATERIALS AND METHODS: To assess the feasibility of the probe in a renal transplant patient, we used the probe in 15 consecutive transplant recipients.
RESULTS: Only 1 Doppler ultrasound was ordered during the 15 admissions compared with scans that are routinely ordered. There were no complications and all probes were removed easily.
CONCLUSIONS: This probe can identify transplanted organs that are threatened owing to flagging or cessation of the blood supply, and allow for immediate intervention. This technique may save precious organs. Further controlled studies are needed to assess the use of the probe in routine clinical practice.

Entities:  

Mesh:

Year:  2011        PMID: 21453229

Source DB:  PubMed          Journal:  Exp Clin Transplant        ISSN: 1304-0855            Impact factor:   0.945


  4 in total

1.  The unsuitability of implantable Doppler probes for the early detection of renal vascular complications - a porcine model for prevention of renal transplant loss.

Authors:  Chris Amdisen; Bente Jespersen; Ulla Møldrup; Anna K Keller
Journal:  PLoS One       Date:  2017-05-25       Impact factor: 3.240

2.  Disability Adjusted Life Years due to Ischaemic Stroke Preventable by Real-Time Stroke Detection-A Cost-Utility Analysis of Hypothetical Stroke Detection Devices.

Authors:  Ludwig Schlemm
Journal:  Front Neurol       Date:  2018-10-01       Impact factor: 4.003

3.  NIRS-based monitoring of kidney graft perfusion.

Authors:  Stepan Maly; Libor Janousek; Radoslav Bortel; Jan Sebek; Jiri Hospodka; Jiri Skapa; Jiri Fronek
Journal:  PLoS One       Date:  2020-12-02       Impact factor: 3.240

4.  The feasibility and applications of non-invasive cardiac output monitoring, thromboelastography and transit-time flow measurement in living-related renal transplantation surgery: results of a prospective pilot observational study.

Authors:  Stephen J Goodyear; James Barnes; Caitlin E Imray; Robert Higgins; For T Lam; S Habib Kashi; Lam C Tan; Christopher He Imray
Journal:  Transplant Res       Date:  2014-08-29
  4 in total

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