Literature DB >> 21452994

Dried blood spots, pharmacokinetic studies and better medicines for children.

Hitesh C Pandya1, Neil Spooner, Hussain Mulla.   

Abstract

Determining circulating drug concentrations in children is an ongoing obstacle to the development of age-appropriate dosing regimens. The requirement for small blood sample volumes in children compared with adults is a significant barrier to obtaining age-specific pharmacokinetic-pharmacodynamic data for this population and hence optimizing the efficacy and safety profile of medicines used by this group. This article discusses the potential for dried blood spot sampling to offer a solution to this issue.

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Year:  2011        PMID： 21452994     DOI： 10.4155/bio.11.19

Source DB:  PubMed          Journal:  Bioanalysis        ISSN： 1757-6180            Impact factor:   2.681


  9 in total

1.  Model-based approaches for ivabradine development in paediatric population, part I: study preparation assessment.

Authors:  Sophie Peigné; François Bouzom; Karl Brendel; Charlotte Gesson; Sylvain Fouliard; Marylore Chenel
Journal:  J Pharmacokinet Pharmacodyn       Date:  2015-11-12       Impact factor: 2.745

2.  Quantification of the Immunosuppressant Tacrolimus on Dried Blood Spots Using LC-MS/MS.

Authors:  Touraj Shokati; Nicholas Bodenberger; Holly Gadpaille; Björn Schniedewind; Alexander A Vinks; Wenlei Jiang; Rita R Alloway; Uwe Christians
Journal:  J Vis Exp       Date:  2015-11-08       Impact factor: 1.355

3.  Model-based approaches for ivabradine development in paediatric population, part II: PK and PK/PD assessment.

Authors:  Sophie Peigné; Sylvain Fouliard; Sophie Decourcelle; Marylore Chenel
Journal:  J Pharmacokinet Pharmacodyn       Date:  2015-11-14       Impact factor: 2.745

4.  Comparison of the quantification of acetaminophen in plasma, cerebrospinal fluid and dried blood spots using high-performance liquid chromatography-tandem mass spectrometry.

Authors:  Rachel R Taylor; Keith L Hoffman; Björn Schniedewind; Claudia Clavijo; Jeffrey L Galinkin; Uwe Christians
Journal:  J Pharm Biomed Anal       Date:  2013-04-16       Impact factor: 3.935

5.  Determination of efavirenz in human dried blood spots by reversed-phase high-performance liquid chromatography with UV detection.

Authors:  Justin T Hoffman; Steven S Rossi; Rowena Espina-Quinto; Scott Letendre; Edmund V Capparelli
Journal:  Ther Drug Monit       Date:  2013-04       Impact factor: 3.681

6.  Dried blood spot UHPLC-MS/MS analysis of oseltamivir and oseltamivircarboxylate--a validated assay for the clinic.

Authors:  Gero P Hooff; Roland J W Meesters; Jeroen J A van Kampen; Nick A van Huizen; Birgit Koch; Asmar F Y Al Hadithy; Teun van Gelder; Albert D M E Osterhaus; Rob A Gruters; Theo M Luider
Journal:  Anal Bioanal Chem       Date:  2011-05-03       Impact factor: 4.142

7.  Validation and Clinical Evaluation of a Novel Method To Measure Miltefosine in Leishmaniasis Patients Using Dried Blood Spot Sample Collection.

Authors:  A E Kip; H Rosing; M J X Hillebrand; S Blesson; B Mengesha; E Diro; A Hailu; J H M Schellens; J H Beijnen; T P C Dorlo
Journal:  Antimicrob Agents Chemother       Date:  2016-03-25       Impact factor: 5.191

Review 8.  The Use of Dried Blood Spots for the Quantification of Antihypertensive Drugs.

Authors:  Alexander Chernonosov
Journal:  Int J Anal Chem       Date:  2018-08-01       Impact factor: 1.885

9.  Determination of blood dexmedetomidine in dried blood spots by LC-MS/MS to screen therapeutic levels in paediatric patients.

Authors:  Liliana Rivera-Espinosa; Alejandra Toledo-López; Juan Luis Chávez-Pacheco; Radamés Alemón-Medina; Josefina Gómez-Garduño; Gustavo Lugo-Goytia; Raquel García-Álvarez; Hugo Juárez-Olguín; Luz María Torres-Espíndola; María-Gabriela Pérez-Guillé
Journal:  PLoS One       Date:  2019-01-14       Impact factor: 3.240
  9 in total

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