| Literature DB >> 21451717 |
Avraham Abramov1, Limor Minai, Dvir Yelin.
Abstract
Spectral imaging, i.e. the acquisition of the spectrum emitted from each sample location, is a powerful tool for a wide variety of applications in science and technology. For biomedical applications, spectral imaging is important for accurate analysis of a biological specimen and for assisting clinical diagnosis, however it could be challenging mainly due to the typically low damage thresholds and strict time constraints. Here, we present a fiber-based technique termed spectrally encoded spectral imaging (SESI), in which a fully emitted spectrum is captured from each resolvable point of a specimen using an additional lateral scanning of the spectrally encoded line. The technique is demonstrated by capturing spectral data cubes of a color print and of a green leaf, and its potential advantage in signal-to-noise ratio is theoretically discussed. Using a miniaturized grating-lens configuration, SESI could be conducted endoscopically, allowing minimally invasive color and spectral imaging in remote locations of the body.Mesh:
Year: 2011 PMID: 21451717 DOI: 10.1364/OE.19.006913
Source DB: PubMed Journal: Opt Express ISSN: 1094-4087 Impact factor: 3.894