Literature DB >> 21451535

Tracing the footsteps of glomerular insulin signaling in diabetic kidney disease.

Gene-Yuan Chang1, Ae Seo Deok Park, Katalin Susztak.   

Abstract

Insufficient insulin secretion and insulin resistance are hallmarks of diabetes. Recent studies indicate that insulin plays an important role in maintaining the glomerular filtration barrier. Mima et al. report that glomeruli of diabetic and obese rats suffer from insulin resistance and altered insulin signaling. Protein kinase C inhibitors are able to overcome insulin resistance, offering new hopes for the treatment of the condition.
© 2011 International Society of Nephrology

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Year:  2011        PMID： 21451535      PMCID： PMC3677185          DOI： 10.1038/ki.2010.559

Source DB:  PubMed          Journal:  Kidney Int        ISSN： 0085-2538            Impact factor:   10.612


  12 in total

Review 1.  Podocytes, glucose and insulin.

Authors:  Gavin I Welsh; Richard J M Coward
Journal:  Curr Opin Nephrol Hypertens       Date:  2010-07       Impact factor: 2.894

Review 2.  Nutrient overload, insulin resistance, and ribosomal protein S6 kinase 1, S6K1.

Authors:  Sung Hee Um; David D'Alessio; George Thomas
Journal:  Cell Metab       Date:  2006-06       Impact factor: 27.287

Review 3.  Protein kinase C and the development of diabetic vascular complications.

Authors:  K J Way; N Katai; G L King
Journal:  Diabet Med       Date:  2001-12       Impact factor: 4.359

4.  Increased renal expression of vascular endothelial growth factor (VEGF) and its receptor VEGFR-2 in experimental diabetes.

Authors:  M E Cooper; D Vranes; S Youssef; S A Stacker; A J Cox; B Rizkalla; D J Casley; L A Bach; D J Kelly; R E Gilbert
Journal:  Diabetes       Date:  1999-11       Impact factor: 9.461

Review 5.  The state of chronic kidney disease, ESRD, and morbidity and mortality in the first year of dialysis.

Authors:  Allan J Collins; Robert N Foley; David T Gilbertson; Shu-Chen Chen
Journal:  Clin J Am Soc Nephrol       Date:  2009-12       Impact factor: 8.237

6.  Genetic variants of the protein kinase C-beta 1 gene and development of end-stage renal disease in patients with type 2 diabetes.

Authors:  Ronald C W Ma; Claudia H T Tam; Ying Wang; Andrea O Luk; Cheng Hu; Xilin Yang; Vincent Lam; Alfred W H Chan; Janice S K Ho; Chun-Chung Chow; Peter C Y Tong; Weiping Jia; Maggie C Y Ng; Wing-Yee So; Juliana C N Chan
Journal:  JAMA       Date:  2010-08-25       Impact factor: 56.272

Review 7.  Redox paradox: insulin action is facilitated by insulin-stimulated reactive oxygen species with multiple potential signaling targets.

Authors:  Barry J Goldstein; Kalyankar Mahadev; Mahadev Kalyankar; Xiangdong Wu
Journal:  Diabetes       Date:  2005-02       Impact factor: 9.461

8.  Podocyte loss and progressive glomerular injury in type II diabetes.

Authors:  M E Pagtalunan; P L Miller; S Jumping-Eagle; R G Nelson; B D Myers; H G Rennke; N S Coplon; L Sun; T W Meyer
Journal:  J Clin Invest       Date:  1997-01-15       Impact factor: 14.808

9.  Glucose-induced reactive oxygen species cause apoptosis of podocytes and podocyte depletion at the onset of diabetic nephropathy.

Authors:  Katalin Susztak; Amanda C Raff; Mario Schiffer; Erwin P Böttinger
Journal:  Diabetes       Date:  2006-01       Impact factor: 9.461

10.  Glomerular-specific alterations of VEGF-A expression lead to distinct congenital and acquired renal diseases.

Authors:  Vera Eremina; Manish Sood; Jody Haigh; András Nagy; Ginette Lajoie; Napoleone Ferrara; Hans-Peter Gerber; Yamato Kikkawa; Jeffrey H Miner; Susan E Quaggin
Journal:  J Clin Invest       Date:  2003-03       Impact factor: 14.808
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  2 in total

1.  Long-term study of the association of adipokines and glucose variability with diabetic complications.

Authors:  Jin Joo Cha; Hye Sook Min; Kitae Kim; Mi Jin Lee; Mi Hwa Lee; Jung Eun Kim; Hye Kyoung Song; Dae Ryong Cha; Young Sun Kang
Journal:  Korean J Intern Med       Date:  2016-11-04       Impact factor: 2.884

2.  Genome-wide Profiling of Urinary Extracellular Vesicle microRNAs Associated With Diabetic Nephropathy in Type 1 Diabetes.

Authors:  Vikas Ghai; Xiaogang Wu; Anjalei Bheda-Malge; Christos P Argyropoulos; José F Bernardo; Trevor Orchard; David Galas; Kai Wang
Journal:  Kidney Int Rep       Date:  2017-12-01
  2 in total

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