Literature DB >> 21450710

hmChIP: a database and web server for exploring publicly available human and mouse ChIP-seq and ChIP-chip data.

Li Chen1, George Wu, Hongkai Ji.   

Abstract

UNLABELLED: hmChIP is a database of genome-wide chromatin immunoprecipitation (ChIP) data in human and mouse. Currently, the database contains 2016 samples from 492 ChIP-seq and ChIP-chip experiments, representing a total of 170 proteins and 11 069 914 protein-DNA interactions. A web server provides interface for database query. Protein-DNA binding intensities can be retrieved from individual samples for user-provided genomic regions. The retrieved intensities can be used to cluster samples and genomic regions to facilitate exploration of combinatorial patterns, cell-type dependencies, and cross-sample variability of protein-DNA interactions. AVAILABILITY: http://jilab.biostat.jhsph.edu/database/cgi-bin/hmChIP.pl.

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Year:  2011        PMID： 21450710      PMCID： PMC3087956          DOI： 10.1093/bioinformatics/btr156

Source DB:  PubMed          Journal:  Bioinformatics        ISSN： 1367-4803            Impact factor:   6.937


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