BACKGROUND: Owing to a reported learning effect in patients with chronic cardiopulmonary disease, performance of at least two six-minute walk tests (6MWT) are recommended as standard practice. Patients with chronic heart failure (CHF) are typically elderly and frail and it is unknown whether current guidelines are practical in a clinical setting. AIMS: The aim of this study was to determine whether repeat performance of 6MWTs in patients with CHF is related to between-test interval or baseline performance. METHODS: This was a multisite observational study enrolling participants entering into heart failure rehabilitation programmes. Participants performed two 6MWTs with randomly allocated inter-test intervals between 15 and 90 minutes. Distance walked in the second test was compared with the first test using a paired t test. RESULTS:Eighty-eight participants (45 females, age 65 ± 14 years) with stable CHF were enrolled. Mean distance walked increased from 301 metres in test 1 to 313 metres in test 2 (p < 0.001). No significant change was recorded between test 1 and test 2 for those whose baseline distance was <300 metres. The interval between tests had no significant effect on the distance walked. CONCLUSION: The change in 6MWT distance was significantly associated with better baseline performance but not with the interval between tests.
RCT Entities:
BACKGROUND: Owing to a reported learning effect in patients with chronic cardiopulmonary disease, performance of at least two six-minute walk tests (6MWT) are recommended as standard practice. Patients with chronic heart failure (CHF) are typically elderly and frail and it is unknown whether current guidelines are practical in a clinical setting. AIMS: The aim of this study was to determine whether repeat performance of 6MWTs in patients with CHF is related to between-test interval or baseline performance. METHODS: This was a multisite observational study enrolling participants entering into heart failure rehabilitation programmes. Participants performed two 6MWTs with randomly allocated inter-test intervals between 15 and 90 minutes. Distance walked in the second test was compared with the first test using a paired t test. RESULTS: Eighty-eight participants (45 females, age 65 ± 14 years) with stable CHF were enrolled. Mean distance walked increased from 301 metres in test 1 to 313 metres in test 2 (p < 0.001). No significant change was recorded between test 1 and test 2 for those whose baseline distance was <300 metres. The interval between tests had no significant effect on the distance walked. CONCLUSION: The change in 6MWT distance was significantly associated with better baseline performance but not with the interval between tests.
Authors: Kenji Matsumoto; Yi Xiao; Shunichi Homma; John L P Thompson; Richard Buchsbaum; Kazato Ito; Stefan D Anker; Min Qian; Marco R Di Tullio Journal: ESC Heart Fail Date: 2020-12-30
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Authors: Tomas Vetrovsky; Michal Siranec; Jiri Parenica; Martin Griva; Jiri Stastny; Jan Precek; Radek Pelouch; Vaclav Bunc; Ales Linhart; Jan Belohlavek Journal: J Transl Med Date: 2017-07-03 Impact factor: 5.531