Literature DB >> 21450207

Physician intervention for medication reduction in a nursing home: the polypharmacy outcomes project.

Bruce K Tamura1, Christina L Bell, Karen Lubimir, Wendy N Iwasaki, Laura A Ziegler, Kamal H Masaki.   

Abstract

OBJECTIVE: To examine the effects of a medication review project by geriatricians and geriatric medicine fellows on polypharmacy in a teaching nursing home.
DESIGN: Quality improvement intervention study
SETTING: Long-term care facility in Honolulu, HI PARTICIPANTS: Seventy-four patients with the Minimum Data Set quality indicator criteria of polypharmacy (9 or more medications). INTERVENTION: Geriatric medicine fellows and faculty reviewed each patient's medication list, consulted the updated Beers Criteria and Epocrates online drug-drug interaction program, and recommended medication changes to the patients' primary care physicians. MEASUREMENTS: Descriptive statistics, including means, standard deviations, and sums of variables were obtained for the number of medications in the following categories: total number, scheduled, pro re nata, high risk, contraindicated, with potential drug-drug interactions, and with no indication.
RESULTS: Of 160 patients residing in a nursing home, 74 were on 9 or more medications. After the intervention, the mean number of medications per patient in the following categories decreased significantly: total number (16.64 to 15.54, P < .001), scheduled (11.3 to 10.99, P < .001), pro re nata (5.33 to 4.56, P < .001), high risk (0.94 to 0.73, P < .001), contraindicated (0.29 to 0.13, P = .004), with potential drug-drug interactions (6.1 to 4.83, P < .001), and with no indication (3.34 to 3.29, P = .045).
CONCLUSION: Polypharmacy in long-term care is prevalent and can lead to increased adverse effects and potentially inappropriate prescriptions. This study demonstrates an effective geriatrician-led intervention that both reduced polypharmacy and provided core competency training for geriatric medicine fellows.
Copyright © 2011 American Medical Directors Association. Published by Elsevier Inc. All rights reserved.

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Year:  2010        PMID: 21450207      PMCID: PMC3102122          DOI: 10.1016/j.jamda.2010.08.013

Source DB:  PubMed          Journal:  J Am Med Dir Assoc        ISSN: 1525-8610            Impact factor:   4.669


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