Literature DB >> 21449929

The evidence for the role of transforming growth factor-beta in the formation of abnormal scarring.

Richard L Chalmers1.   

Abstract

The complex biological and physiological mechanisms that result in poor quality scarring are still not fully understood. This review looks at current evidence of the role of transforming growth factor-beta (TGFβ) in this pathological process.
© 2011 The Author. © 2011 Blackwell Publishing Ltd and Medicalhelplines.com Inc.

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Year:  2011        PMID: 21449929      PMCID: PMC7950816          DOI: 10.1111/j.1742-481X.2011.00771.x

Source DB:  PubMed          Journal:  Int Wound J        ISSN: 1742-4801            Impact factor:   3.315


  44 in total

Review 1.  Suppressor and oncogenic roles of transforming growth factor-beta and its signaling pathways in tumorigenesis.

Authors:  E Piek; A B Roberts
Journal:  Adv Cancer Res       Date:  2001       Impact factor: 6.242

Review 2.  Role of platelet-derived growth factor in wound healing.

Authors:  G F Pierce; T A Mustoe; B W Altrock; T F Deuel; A Thomason
Journal:  J Cell Biochem       Date:  1991-04       Impact factor: 4.429

3.  Hypertrophic response and keloid diathesis: two very different forms of scar.

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4.  Brief exposure to high-dose transforming growth factor-beta1 enhances periosteal chondrogenesis in vitro: a preliminary report.

Authors:  Yasushi Miura; Javad Parvizi; James S Fitzsimmons; Shawn W O'Driscoll
Journal:  J Bone Joint Surg Am       Date:  2002-05       Impact factor: 5.284

5.  Biochemical composition of the connective tissue in keloids and analysis of collagen metabolism in keloid fibroblast cultures.

Authors:  R P Abergel; D Pizzurro; C A Meeker; G Lask; L Y Matsuoka; R R Minor; M L Chu; J Uitto
Journal:  J Invest Dermatol       Date:  1985-05       Impact factor: 8.551

6.  Role of elevated plasma transforming growth factor-beta1 levels in wound healing.

Authors:  M Shah; D Revis; S Herrick; R Baillie; S Thorgeirson; M Ferguson; A Roberts
Journal:  Am J Pathol       Date:  1999-04       Impact factor: 4.307

7.  The effect of TGF-beta on keloid fibroblast proliferation and collagen synthesis.

Authors:  D A Bettinger; D R Yager; R F Diegelmann; I K Cohen
Journal:  Plast Reconstr Surg       Date:  1996-10       Impact factor: 4.730

8.  Transcription and expression of transforming growth factor type beta in the skin of progressive systemic sclerosis: a mediator of fibrosis?

Authors:  M Gruschwitz; P U Müller; N Sepp; E Hofer; A Fontana; G Wick
Journal:  J Invest Dermatol       Date:  1990-02       Impact factor: 8.551

9.  Neutralisation of TGF-beta 1 and TGF-beta 2 or exogenous addition of TGF-beta 3 to cutaneous rat wounds reduces scarring.

Authors:  M Shah; D M Foreman; M W Ferguson
Journal:  J Cell Sci       Date:  1995-03       Impact factor: 5.285

10.  Transforming growth factor-beta 1 induces alpha-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts.

Authors:  A Desmoulière; A Geinoz; F Gabbiani; G Gabbiani
Journal:  J Cell Biol       Date:  1993-07       Impact factor: 10.539

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  14 in total

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Journal:  Adv Wound Care (New Rochelle)       Date:  2015-03-01       Impact factor: 4.730

3.  The clinical dynamic changes of macrophage phenotype and function in different stages of human wound healing and hypertrophic scar formation.

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Journal:  Int Wound J       Date:  2018-11-15       Impact factor: 3.315

Review 4.  Epithelial-mesenchymal transition, TGF-β, and osteopontin in wound healing and tissue remodeling after injury.

Authors:  Cynthia E Weber; Neill Y Li; Philip Y Wai; Paul C Kuo
Journal:  J Burn Care Res       Date:  2012 May-Jun       Impact factor: 1.845

5.  Keloid scarring: understanding the genetic basis, advances, and prospects.

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Journal:  Arch Plast Surg       Date:  2012-05-10

6.  Keloid Pathogenesis: Potential Role of Cellular Fibronectin with the EDA Domain.

Authors:  Jonathan P Andrews; Jaana Marttala; Edward Macarak; Joel Rosenbloom; Jouni Uitto
Journal:  J Invest Dermatol       Date:  2015-02-16       Impact factor: 8.551

7.  Effect of P144® (Anti-TGF-β) in an "In Vivo" Human Hypertrophic Scar Model in Nude Mice.

Authors:  Shan Shan Qiu; Javier Dotor; Bernardo Hontanilla
Journal:  PLoS One       Date:  2015-12-31       Impact factor: 3.240

8.  Honokiol Alleviates Hypertrophic Scar by Targeting Transforming Growth Factor-β/Smad2/3 Signaling Pathway.

Authors:  Danyang Zhao; Yu Wang; Chao Du; Shengzhou Shan; Yifan Zhang; Zijing Du; Dong Han
Journal:  Front Pharmacol       Date:  2017-04-19       Impact factor: 5.810

9.  Human adipose-derived stem cells inhibit bioactivity of keloid fibroblasts.

Authors:  Xiuxia Wang; Yan Ma; Zhen Gao; Jun Yang
Journal:  Stem Cell Res Ther       Date:  2018-02-21       Impact factor: 6.832

10.  The anti-scar effects of basic fibroblast growth factor on the wound repair in vitro and in vivo.

Authors:  Hong-Xue Shi; Cai Lin; Bei-Bei Lin; Zhou-Guang Wang; Hong-Yu Zhang; Fen-Zan Wu; Yi Cheng; Li-Jun Xiang; Di-Jiong Guo; Xu Luo; Guo-You Zhang; Xiao-Bing Fu; Saverio Bellusci; Xiao-Kun Li; Jian Xiao
Journal:  PLoS One       Date:  2013-04-02       Impact factor: 3.240

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