Literature DB >> 21449534

A mitochondrial-targeted two-photon probe for zinc ion.

Goutam Masanta1, Chang Su Lim, Hyung Joong Kim, Ji Hee Han, Hwan Myung Kim, Bong Rae Cho.   

Abstract

We report a two-photon probe (SZn-Mito) for mitochondrial zinc ions ([Zn2+]m). This probe shows a 7-fold enhancement of two-photon-excited fluorescence in response to Zn2+ with a dissociation constant (Kd(TP)) of 3.1 ± 0.1 nM and pH insensitivity in the biologically relevant range, allowing the detection of [Zn2+]m in a rat hippocampal slice at a depth of 100−200 μm without interference from other metal ions through the use of two-photon microscopy.

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Year:  2011        PMID： 21449534     DOI： 10.1021/ja200444t

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


  19 in total

1.  Zn(II)-coordination modulated ligand photophysical processes - the development of fluorescent indicators for imaging biological Zn(II) ions.

Authors:  Lei Zhu; Zhao Yuan; J Tyler Simmons; Kesavapillai Sreenath
Journal:  RSC Adv       Date:  2014-01-01       Impact factor: 3.361

2.  Quantitative imaging of mitochondrial and cytosolic free zinc levels in an in vitro model of ischemia/reperfusion.

Authors:  Bryan J McCranor; Rebecca A Bozym; Michele I Vitolo; Carol A Fierke; Linda Bambrick; Brian M Polster; Gary Fiskum; Richard B Thompson
Journal:  J Bioenerg Biomembr       Date:  2012-03-20       Impact factor: 2.945

3.  Reaction-based fluorescent sensor for investigating mobile Zn2+ in mitochondria of healthy versus cancerous prostate cells.

Authors:  Wen Chyan; Daniel Y Zhang; Stephen J Lippard; Robert J Radford
Journal:  Proc Natl Acad Sci U S A       Date:  2013-12-12       Impact factor: 11.205

4.  A FRET-based indicator for imaging mitochondrial zinc ions.

Authors:  Kesavapillai Sreenath; John R Allen; Michael W Davidson; Lei Zhu
Journal:  Chem Commun (Camb)       Date:  2011-09-19       Impact factor: 6.222

5.  Integrated and passive 1,2,3-triazolyl groups in fluorescent indicators for zinc(II) ions: thermodynamic and kinetic evaluations.

Authors:  J Tyler Simmons; John R Allen; Deborah R Morris; Ronald J Clark; Cathy W Levenson; Michael W Davidson; Lei Zhu
Journal:  Inorg Chem       Date:  2013-04-26       Impact factor: 5.165

6.  Balance between fluorescence enhancement and association affinity in fluorescent heteroditopic indicators for imaging zinc ion in living cells.

Authors:  Gui-Chao Kuang; John R Allen; Michelle A Baird; Brian T Nguyen; Lu Zhang; Thomas J Morgan; Cathy W Levenson; Michael W Davidson; Lei Zhu
Journal:  Inorg Chem       Date:  2011-09-12       Impact factor: 5.165

7.  A mitochondria-targeted ratiometric two-photon fluorescent probe for biological zinc ions detection.

Authors:  Peng Ning; Jiacheng Jiang; Longchun Li; Shuxin Wang; Haizhu Yu; Yan Feng; Manzhou Zhu; Buchang Zhang; Hang Yin; Qingxiang Guo; Xiangming Meng
Journal:  Biosens Bioelectron       Date:  2015-10-26       Impact factor: 10.618

Review 8.  Two-photon probes for in vivo multicolor microscopy of the structure and signals of brain cells.

Authors:  Clément Ricard; Erica D Arroyo; Cynthia X He; Carlos Portera-Cailliau; Gabriel Lepousez; Marco Canepari; Daniel Fiole
Journal:  Brain Struct Funct       Date:  2018-05-11       Impact factor: 3.270

9.  New sensors for quantitative measurement of mitochondrial Zn(2+).

Authors:  J Genevieve Park; Yan Qin; Domenico F Galati; Amy E Palmer
Journal:  ACS Chem Biol       Date:  2012-08-10       Impact factor: 5.100

Review 10.  Subcellular localised small molecule fluorescent probes to image mobile Zn2.

Authors:  Le Fang; Michael Watkinson
Journal:  Chem Sci       Date:  2020-10-09       Impact factor: 9.825
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