Literature DB >> 21448824

[Therapeutic angiogenesis using gene transfer and stem cell therapy in peripheral artery disease].

S Nikol1.   

Abstract

The world-wide largest angiogenesis gene therapy trial in 525 patients suffering from critical limb ischemia and treated with the non-viral gene construct for fibroblast growth factor (NV1FGF) or placebo was negative for all endpoints. Also, stem cell or progenitor cell therapy did no reveal clinical benefit in patients with peripheral artery disease. Data from large randomized placebo-controlled are still not available. © Georg Thieme Verlag KG Stuttgart · New York.

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Year:  2011        PMID: 21448824     DOI: 10.1055/s-0031-1274561

Source DB:  PubMed          Journal:  Dtsch Med Wochenschr        ISSN: 0012-0472            Impact factor:   0.628


  2 in total

Review 1.  Gene Therapy of Chronic Limb-Threatening Ischemia: Vascular Medical Perspectives.

Authors:  Florian Simon; Mansur Duran; Waseem Garabet; Hubert Schelzig; Michael Jacobs; Alexander Gombert
Journal:  J Clin Med       Date:  2022-02-26       Impact factor: 4.241

2.  Long-term MRI tracking of dual-labeled adipose-derived stem cells homing into mouse carotid artery injury.

Authors:  Jin-Bao Qin; Kang-An Li; Xiang-Xiang Li; Qing-Song Xie; Jia-Ying Lin; Kai-Chuang Ye; Mi-Er Jiang; Gui-Xiang Zhang; Xin-Wu Lu
Journal:  Int J Nanomedicine       Date:  2012-10-02
  2 in total

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